pexidartinib-resistant FLT3 mutants [plasma membrane]

Stable Identifier
R-HSA-9699534
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
25847190 Characterizing and Overriding the Structural Mechanism of the Quizartinib-Resistant FLT3 "Gatekeeper" F691L Mutation with PLX3397

Smith, CC, Zhang, C, Lin, KC, Lasater, EA, Zhang, Y, Massi, E, Damon, LE, Pendleton, M, Bashir, A, Sebra, R, Perl, A, Kasarskis, A, Shellooe, R, Tsang, G, Carias, H, Powell, B, Burton, EA, Matusow, B, Zhang, J, Spevak, W, Ibrahim, PN, Le, MH, Hsu, HH, Habets, G, West, BL, Bollag, G, Shah, NP

2015
26108694 FLT3 D835 mutations confer differential resistance to type II FLT3 inhibitors

Smith, CC, Lin, K, Stecula, A, Sali, A, Shah, NP

Leukemia 2015
Participants
Participant Of
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
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