HCMV Genome Replication Completion

Stable Identifier
R-HSA-9698926
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Human cytomegalovirus
Compartment
nucleoplasm
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HCMV Genome Replication Completion
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Human Cytomegalovirus (HCMV) DNA synthesis may start replication using a theta form initiating at an origin and generating a replication bubble before switching to a rolling circle mode of replication. The architecture of replicating DNA is consistent with concatemeric structures generated by rolling circle form of replication, and this is the likely template for the genome encapsidation. Replication ends with the association of the Terminase complex and the threading of the completed genome into the procapsid

Literature References
PubMed ID Title Journal Year
  Fields Virology

Knipe, DM, Howley, PM

  2013
Participants
Input
Output
Participant Of
hasEvent
Disease
Name Identifier Synonyms
viral infectious disease 934 Viral disease, virus infection, virus infection
Authored
Gillespie, ME  (2018-11-28)
Reviewed
Caposio, P  (2019-10-18)
Streblow, DN  (2019-10-18)
Created
Gillespie, ME  (2019-02-12)
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