HCMV Genome Replication Completion

Stable Identifier
R-HSA-9698926
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Human cytomegalovirus
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Human Cytomegalovirus (HCMV) DNA synthesis may start replication using a theta form initiating at an origin and generating a replication bubble before switching to a rolling circle mode of replication. The architecture of replicating DNA is consistent with concatemeric structures generated by rolling circle form of replication, and this is the likely template for the genome encapsidation. Replication ends with the association of the Terminase complex and the threading of the completed genome into the procapsid
Literature References
PubMed ID Title Journal Year
  Fields Virology

Knipe, DM, Howley, PM

  2013
Participants
Participates
Disease
Name Identifier Synonyms
viral infectious disease DOID:934 Viral disease, virus infection, virus infection
Authored
Reviewed
Created
Cite Us!