p-STAT5 binds the CDKN1A gene

Stable Identifier
R-HSA-9698041
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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p-STAT5 binds to its cognate sites in the promoter of the CDKN1A gene in a FLT3-ITD-dependent manner as assessed by reporter assay and electrophoretic mobility shift assay (EMSA) (Takahashi et al, 2004).

Literature References
PubMed ID Title Journal Year
15003515 Flt3 mutation activates p21WAF1/CIP1 gene expression through the action of STAT5

Takahashi, S, Harigae, H, Kaku, M, Sasaki, T, Licht, JD

Biochem. Biophys. Res. Commun. 2004
Participants
Participant Of
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
Authored
Reviewed
Created
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