LprG dissociates from LAM,LM

Stable Identifier
R-HSA-9697070
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Lipoarabinomannan carrier protein (LprG) dissociates from lipoarabinomannan (LAM) and lipomannan (LM) in the DIM/DIP cell wall layer after the transport from the Mtb cytosol (Shukla et al. 2014, Martinot et al. 2016).
Literature References
PubMed ID Title Journal Year
26751071 Mycobacterial Metabolic Syndrome: LprG and Rv1410 Regulate Triacylglyceride Levels, Growth Rate and Virulence in Mycobacterium tuberculosis

Iqbal, J, Layre, E, Seeliger, JC, Martinot, AJ, Moody, DB, Hussain, MM, Cheng, TY, Bai, L, Tsai, JH, Annand, JW, Farrow, M, Sullivan, ZA, Rubin, EJ, Sacchettini, J

PLoS Pathog. 2016
25356793 Mycobacterium tuberculosis lipoprotein LprG binds lipoarabinomannan and determines its cell envelope localization to control phagolysosomal fusion

Harding, CV, Banaei, N, Boom, WH, Shi, L, McDonald, D, Athman, JJ, Jackson, M, Shukla, S, Wearsch, PA, Richardson, ET

PLoS Pathog. 2014
Participants
Participates
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Reviewed
Created
Cite Us!