LprG dissociates from LAM,LM

Stable Identifier
R-HSA-9697070
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
peptidoglycan-based cell wall
ReviewStatus
5/5
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LprG dissociates from LAM,LM
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Lipoarabinomannan carrier protein (LprG) dissociates from lipoarabinomannan (LAM) and lipomannan (LM) in the DIM/DIP cell wall layer after the transport from the Mtb cytosol (Shukla et al. 2014, Martinot et al. 2016).
Literature References
PubMed ID Title Journal Year
26751071 Mycobacterial Metabolic Syndrome: LprG and Rv1410 Regulate Triacylglyceride Levels, Growth Rate and Virulence in Mycobacterium tuberculosis

Martinot, AJ, Farrow, M, Bai, L, Layre, E, Cheng, TY, Tsai, JH, Iqbal, J, Annand, JW, Sullivan, ZA, Hussain, MM, Sacchettini, J, Moody, DB, Seeliger, JC, Rubin, EJ

PLoS Pathog. 2016
25356793 Mycobacterium tuberculosis lipoprotein LprG binds lipoarabinomannan and determines its cell envelope localization to control phagolysosomal fusion

Shukla, S, Richardson, ET, Athman, JJ, Shi, L, Wearsch, PA, McDonald, D, Banaei, N, Boom, WH, Jackson, M, Harding, CV

PLoS Pathog. 2014
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Cross References
Mondo
Authored
Stephan, R  (2019-02-06)
Reviewed
Deffur, A  (2019-10-23)
Wilkinson, RJ  (2019-10-23)
Created
Jassal, B  (2020-08-05)
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