Reactome | RND2 [plasma membrane]

RND2 [plasma membrane]

Stable Identifier

R-HSA-9696269

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Rho-related GTP-binding protein RhoN, RND2_HUMAN, RHO7

Locations in the PathwayBrowser for interactor UniProt:O43157 PLXNB1

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Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - RND2 GTPase cycle (Homo sapiens)
        
        RND2 binds GTP (Homo sapiens)
        
        RND2 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P52198 RND2

Gene Names

RND2, ARHN, RHO7

Chain

chain:1-224, propeptide:225-227

Reference Genes

BioGPS Gene:8153 RND2

COSMIC (genes):RND2 RND2

CTD Gene:8153 RND2

dbSNP Gene:8153 RND2

ENSEMBL:ENSG00000108830 RND2

ENSEMBL_homo_sapiens_GENE:ENSG00000108830.11 RND2

HGNC:18315 RND2

KEGG Gene (Homo sapiens):8153 RND2

Monarch:8153 RND2

NCBI Gene:8153 RND2

OMIM:601555 RND2

UCSC:P52198 RND2

Reference Transcript

RefSeq:NM_005440.4 RND2

Other Identifiers

11724854_at

11724855_at

16834559

213467_PM_at

213467_at

214393_PM_at

214393_at

3722359

3722360

3722361

3722362

3722363

3722364

3722365

3722366

3722367

3722368

3722369

3722370

41082_at

55998_at

606_at

644_at

8007454

8153

83972_at

A_14_P134266

A_23_P434807

A_33_P3382860

GE57804

GO:0000166

GO:0002080

GO:0003824

GO:0003924

GO:0005515

GO:0005525

GO:0005768

GO:0005769

GO:0005829

GO:0005886

GO:0007010

GO:0007015

GO:0007165

GO:0007264

GO:0016020

GO:0016477

GO:0016787

GO:0019901

GO:0023052

GO:0030154

GO:0031410

GO:0043226

GO:0048668

GO:0048672

GO:0048856

GO:0048870

HMNXSV003057133

Hs.21964.0.A1_3p_at

Hs.99034.0.S2_3p_at

ILMN_1736533

L78833_cds2_at

PH_hs_0025497

PH_hs_0038165

TC17000546.hg

Participates

as a component of

RND2:GTP [plasma membrane] (Homo sapiens)

as an input of

RND2 binds GTP (Homo sapiens)

Inferred To

RND2 [plasma membrane] (Bos taurus)

RND2 [plasma membrane] (Canis familiaris)

RND2 [plasma membrane] (Gallus gallus)

RND2 [plasma membrane] (Mus musculus)

RND2 [plasma membrane] (Saccharomyces cerevisiae)

RND2 [plasma membrane] (Schizosaccharomyces pombe)

RND2 [plasma membrane] (Sus scrofa)

rnd2 [plasma membrane] (Danio rerio)

Homologues of RND2 [plasma membrane] (Saccharomyces cerevisiae)

Homologues of RND2 [plasma membrane] (Schizosaccharomyces pombe)

Rnd2 [plasma membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_005431.1

OpenTargets

ENSG00000108830

HPA

ENSG00000108830-RND2

GeneCards

P52198

Ensembl

ENSP00000466680, ENSG00000108830, ENST00000587250

PRO

P52198

Pharos - Targets

P52198

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96K76 USP47	1	USP47 [nucleoplasm] (R-HSA-5696961)	0.589	3
UniProt:O43157 PLXNB1	2	PLXNB1 [plasma membrane] (R-HSA-3008951) p-Y-PLXNB1 [plasma membrane] (R-HSA-419609)	0.558	2
UniProt:O15031 PLXB2			0.558	2
UniProt:Q8R511	1	Fnbp1 [cytosol] (R-RNO-8862261)	0.524	2

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