Reactome | RND3 [plasma membrane]

RND3 [plasma membrane]

Stable Identifier

R-HSA-9696265

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Rho-related GTP-binding protein RhoE, RND3_HUMAN, RHOE, RHO8

Locations in the PathwayBrowser for interactor UniProt:O43157 PLXNB1

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase cycle (Homo sapiens)
      - RND3 GTPase cycle (Homo sapiens)
        
        RND3 binds GTP (Homo sapiens)
        
        RND3 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P61587 RND3

Gene Names

RND3, ARHE, RHO8, RHOE

Chain

chain:1-241, propeptide:242-244

Reference Genes

BioGPS Gene:390 RND3

COSMIC (genes):RND3 RND3

CTD Gene:390 RND3

dbSNP Gene:390 RND3

ENSEMBL:ENSG00000115963 RND3

ENSEMBL_homo_sapiens_GENE:ENSG00000115963.14 RND3

HGNC:671 RND3

KEGG Gene (Homo sapiens):390 RND3

Monarch:390 RND3

NCBI Gene:390 RND3

OMIM:602924 RND3

UCSC:P61587 RND3

Reference Transcript

Other Identifiers

11737760_s_at

11753427_a_at

11756465_s_at

16903491

212724_PM_at

212724_at

2580801

2580803

2580804

2580805

2580806

2580807

2580810

2580814

2580817

2580818

2580819

2580820

2580821

35803_at

390

8055688

A_23_P142849

GE58822

GO:0000139

GO:0000166

GO:0003824

GO:0003924

GO:0005515

GO:0005525

GO:0005794

GO:0005829

GO:0005886

GO:0005925

GO:0007010

GO:0007015

GO:0007155

GO:0007165

GO:0007264

GO:0016020

GO:0016477

GO:0016787

GO:0019901

GO:0023052

GO:0030036

GO:0043226

GO:0048870

HMNXSV003050227

Hs.6838.0.S2_3p_at

ILMN_1759513

PH_hs_0000694

S82240_at

TC02002419.hg

Participates

as a component of

RND3:GTP [plasma membrane] (Homo sapiens)

as an input of

RND3 binds GTP (Homo sapiens)

Inferred To

rnd3a [plasma membrane] (Danio rerio)

Homologues of RND3 [plasma membrane] (Saccharomyces cerevisiae)

Homologues of RND3 [plasma membrane] (Schizosaccharomyces pombe)

RND3 [plasma membrane] (Bos taurus)

RND3 [plasma membrane] (Canis familiaris)

RND3 [plasma membrane] (Gallus gallus)

RND3 [plasma membrane] (Mus musculus)

RND3 [plasma membrane] (Rattus norvegicus)

RND3 [plasma membrane] (Saccharomyces cerevisiae)

RND3 [plasma membrane] (Schizosaccharomyces pombe)

RND3 [plasma membrane] (Sus scrofa)

rnd3 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_005159.1, NP_001241667.1

OpenTargets

ENSG00000115963

HPA

ENSG00000115963-RND3

GeneCards

P61587

Ensembl

ENSP00000263895, ENSG00000115963, ENST00000375734, ENSP00000364886, ENST00000263895

PRO

P61587

Pharos - Targets

P61587

HMDB Protein

HMDBP08561

PDB

8BFC, 4BG6, 7OBC, 2V55, 8B2K, 7OBD, 1M7B

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43157 PLXNB1	2	PLXNB1 [plasma membrane] (R-HSA-3008951) p-Y-PLXNB1 [plasma membrane] (R-HSA-419609)	0.676	3
UniProt:P63104 YWHAZ	2	YWHAZ [nucleoplasm] (R-HSA-450469) YWHAZ [cytosol] (R-HSA-206099)	0.655	11
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.59	3
UniProt:O15031 PLXB2			0.558	2
UniProt:Q9NWQ9 CN119			0.556	3
UniProt:O94827-4 PLEKHG5			0.556	3
UniProt:Q9BU20 CPLN2			0.556	3