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Protein E forms a homopentamer
Stable Identifier
R-HSA-9694452
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Severe acute respiratory syndrome coronavirus 2
Compartment
endoplasmic reticulum lumen
ReviewStatus
5/5
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Disease (Homo sapiens)
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SARS-CoV-2 Infection (Homo sapiens)
Late SARS-CoV-2 Infection Events (Homo sapiens)
Translation of Structural Proteins (Homo sapiens)
Maturation of protein E (Homo sapiens)
Protein E forms a homopentamer (Homo sapiens)
General
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
SARS-CoV-2 protein E forms a pentamer of monomers without disulfide bonds (Mandala et al, 2020).
Literature References
PubMed ID
Title
Journal
Year
33177698
Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers
Dregni, AJ
,
Mandala, VS
,
McKay, MJ
,
Kolocouris, A
,
Hong, M
,
Shcherbakov, AA
Nat Struct Mol Biol
2020
Participants
Input
x 5
Ub-3xPalmC-E [endoplasmic reticulum lumen]
(Severe acute respiratory syndrome coronavirus 2)
Output
Ub-3xPalmC-E pentamer [endoplasmic reticulum membrane]
(Severe acute respiratory syndrome coronavirus 2)
Participates
as an event of
Maturation of protein E (Homo sapiens)
Disease
Name
Identifier
Synonyms
COVID-19
DOID:0080600
2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
Authored
Stephan, R (2020-08-28)
Reviewed
Acencio, ML (2020-09-09)
Created
Cook, J (2020-07-07)
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