Glycosylated M localizes to the Golgi membrane

Stable Identifier
R-HSA-9694367
Type
Reaction [omitted]
Species
Homo sapiens
Related Species
Severe acute respiratory syndrome coronavirus 2
Compartment
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This COVID-19 event has been created by a combination of computational inference (see https://reactome.org/documentation/inferred-events) from SARS-CoV-1 data and manual curation, as described in the summation for the overall SARS-CoV-2 infection pathway.

Protein M accumulates in the Golgi complex and recruits Spike protein to the sites of virus assembly and budding in the ERGIC (Voss et al, 2009).

Literature References
PubMed ID Title Journal Year
19534833 Studies on membrane topology, N-glycosylation and functionality of SARS-CoV membrane protein

Voss, D, Pfefferle, S, Drosten, C, Stevermann, L, Traggiai, E, Lanzavecchia, A, Becker, S

Virol. J. 2009
Participants
Participates
Inferred From
Disease
Name Identifier Synonyms
COVID-19 DOID:0080600 2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
Authored
Reviewed
Created
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