3a is externalized together with membrane structures

Stable Identifier
R-HSA-9694308
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Severe acute respiratory syndrome coronavirus 2
Compartment
plasma membrane, extracellular region
ReviewStatus
5/5
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3a is externalized together with membrane structures
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This COVID-19 event has been created by a combination of computational inference (see https://reactome.org/documentation/inferred-events) from SARS-CoV-1 data and manual curation, as described in the summation for the overall SARS-CoV-2 infection pathway.

Membranous structures containing protein 3a are shed from the cell membrane (Huang et al, 2006)
Literature References
PubMed ID Title Journal Year
16352545 Severe acute respiratory syndrome coronavirus 3a protein is released in membranous structures from 3a protein-expressing cells and infected cells

Huang, C, Makino, S, Peters, CJ, Ito, N, Narayanan, K

J. Virol. 2006
Participants
Input
Output
Participates
as an event of
Inferred From
3a is externalized together with membrane structures (Homo sapiens)
Disease
Name Identifier Synonyms
COVID-19 DOID:0080600 2019 Novel Coronavirus (2019-nCoV), Wuhan seafood market pneumonia virus infection, 2019-nCoV infection, Wuhan coronavirus infection
Authored
Stephan, R  (2020-08-28)
Reviewed
Acencio, ML  (2020-09-09)
Created
Cook, J  (2020-07-07)
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