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small molecule inhibitors of RIPK1, RIPK3 [cytosol]
Stable Identifier
R-HSA-9694028
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
cytosol
Synonyms
sorafenib, ponatinib
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Mus musculus
Rattus norvegicus
Sus scrofa
Expand all
Programmed Cell Death (Bos taurus)
Regulated Necrosis (Bos taurus)
RIPK1-mediated regulated necrosis (Bos taurus)
RIPK1 is phosphorylated (Bos taurus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Bos taurus)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
RIPK3 is phosphorylated (Bos taurus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Bos taurus)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
Regulation of necroptotic cell death (Bos taurus)
Small molecule inhibitor binds RIPK1, RIPK3 (Bos taurus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Bos taurus)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
Programmed Cell Death (Canis familiaris)
Regulated Necrosis (Canis familiaris)
RIPK1-mediated regulated necrosis (Canis familiaris)
RIPK1 is phosphorylated (Canis familiaris)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Canis familiaris)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
RIPK3 is phosphorylated (Canis familiaris)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Canis familiaris)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
Regulation of necroptotic cell death (Canis familiaris)
Small molecule inhibitor binds RIPK1, RIPK3 (Canis familiaris)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Canis familiaris)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
Programmed Cell Death (Homo sapiens)
Regulated Necrosis (Homo sapiens)
RIPK1-mediated regulated necrosis (Homo sapiens)
RIPK1 is phosphorylated (Homo sapiens)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Homo sapiens)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
RIPK3 is phosphorylated (Homo sapiens)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Homo sapiens)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
Regulation of necroptotic cell death (Homo sapiens)
Small molecule inhibitor binds RIPK1, RIPK3 (Homo sapiens)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Homo sapiens)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
Programmed Cell Death (Mus musculus)
Regulated Necrosis (Mus musculus)
RIPK1-mediated regulated necrosis (Mus musculus)
RIPK1 is phosphorylated (Mus musculus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Mus musculus)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
RIPK3 is phosphorylated (Mus musculus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Mus musculus)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
Regulation of necroptotic cell death (Mus musculus)
Small molecule inhibitor binds RIPK1, RIPK3 (Mus musculus)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Mus musculus)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
Programmed Cell Death (Rattus norvegicus)
Regulated Necrosis (Rattus norvegicus)
RIPK1-mediated regulated necrosis (Rattus norvegicus)
RIPK1 is phosphorylated (Rattus norvegicus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Rattus norvegicus)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
RIPK3 is phosphorylated (Rattus norvegicus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Rattus norvegicus)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
Regulation of necroptotic cell death (Rattus norvegicus)
Small molecule inhibitor binds RIPK1, RIPK3 (Rattus norvegicus)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Rattus norvegicus)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
Programmed Cell Death (Sus scrofa)
Regulated Necrosis (Sus scrofa)
RIPK1-mediated regulated necrosis (Sus scrofa)
RIPK1 is phosphorylated (Sus scrofa)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Sus scrofa)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
RIPK3 is phosphorylated (Sus scrofa)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Sus scrofa)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
Regulation of necroptotic cell death (Sus scrofa)
Small molecule inhibitor binds RIPK1, RIPK3 (Sus scrofa)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Sus scrofa)
small molecule inhibitors of RIPK1, RIPK3 [cytosol] (Homo sapiens)
Participants
members
ponatinib [cytosol]
sorafenib [cytosol]
pazopanib [cytosol]
Participates
as an input of
Small molecule inhibitor binds RIPK1, RIPK3 (Sus scrofa)
Small molecule inhibitor binds RIPK1, RIPK3 (Bos taurus)
Small molecule inhibitor binds RIPK1, RIPK3 (Canis familiaris)
Small molecule inhibitor binds RIPK1, RIPK3 (Rattus norvegicus)
Small molecule inhibitor binds RIPK1, RIPK3 (Mus musculus)
Small molecule inhibitor binds RIPK1, RIPK3 (Homo sapiens)
as a component of
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Canis familiaris)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Sus scrofa)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Bos taurus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Rattus norvegicus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Mus musculus)
RIPK1:RIPK3:sorafenib, ponatinib, pazopanib [cytosol] (Homo sapiens)
Disease
Name
Identifier
Synonyms
inflammation
DOID:0000061
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