Unknown sepiapterin synthase transforms PTHP to sepiapterin

Stable Identifier
R-HSA-9693722
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Unknown sepiapterin synthase transforms PTHP to sepiapterin
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In an alternative salvage pathway for BH4 synthesis, dyspropterin (PTHP) may be transformed to sepiapterin, possibly non-enzymatically or by an unknown sepiapterin synthase enzyme (Crabtree & Channon 2011).
Literature References
PubMed ID Title Journal Year
21550412 Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease

Channon, KM, Crabtree, MJ

Nitric Oxide 2011
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Catalyst Activity

oxidoreductase activity of sepiapterin synthase [cytosol]

Physical Entity
sepiapterin synthase [cytosol] (Homo sapiens)
Activity
oxidoreductase activity (GO:0016491)
Authored
Jassal, B  (2020-07-06)
Reviewed
D'Eustachio, P  (2020-07-06)
Created
Jassal, B  (2020-07-06)
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