Active GTP-bound RHOD binds PAK5 and recruits it to the mitochondrial outer membrane (Wu and Frost 2006).GTP-bound RHOD also binds HINT2 at the mitochondrial outer membrane, which triggers mitochondrial Ca2+ influx (Chen et al. 2017, supported by Bagci et al. 2020). VRK2, which can localize to the mitochondrial outer membrane was reported to bind active RHOD by Bagci et al. 2020 and is annotated as a candidate effector.
Hu, Z, Chen, L, Wang, W, Yang, Q, Xie, H, Zhou, D, Zhang, L, Yao, H, Zhou, L, Song, W, Zheng, S, Ju, B, Sun, Q
Tran, V, Gingras, AC, Elkholi, IE, Robert, A, Boulais, J, Faubert, D, Dubé, N, Hipfner, DR, Cote, JF, Lin, ZY, Bagci, H, Sriskandarajah, N, Thibault, MP
Frost, JA, Wu, X
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