CDC42 binds effectors at the ER membrane

Stable Identifier
R-HSA-9692809
Type
Reaction
Species
Homo sapiens
Compartment
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Activated GTP-bound CDC42 binds to kinectin (KTN1) at the endoplasmic reticulum membrane (Hotta et al. 1996).

Active CDC42 also binds the following candidate effectors at the endoplasmic reticulum membrane identified in the screen by Bagci et al. 2020:
LBR (Bagci et al. 2020)
YKT6 (Bagci et al. 2020)

Literature References
PubMed ID Title Journal Year
31871319 Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

Tran, V, Gingras, AC, Elkholi, IE, Robert, A, Boulais, J, Faubert, D, Dubé, N, Hipfner, DR, Cote, JF, Lin, ZY, Bagci, H, Sriskandarajah, N, Thibault, MP

Nat. Cell Biol. 2020
8769096 Interaction of the Rho family small G proteins with kinectin, an anchoring protein of kinesin motor

Mino, A, Kohno, H, Hotta, K, Takai, Y, Tanaka, K

Biochem. Biophys. Res. Commun. 1996
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