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p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane]
Stable Identifier
R-HSA-9691155
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
FLT3 signaling in disease (Homo sapiens)
Signaling by FLT3 ITD and TKD mutants (Homo sapiens)
Constitutive phosphorylation of FLT3 mutants (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
FLT3 mutant dimers bind GRB2 (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
FLT3 mutant dimers:GRB2 bind SOS1 (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:SOS1 [plasma membrane] (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
FLT3 mutants phosphorylate GAB2 (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:GAB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:p-Y GAB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
FLT3 mutants recruit PIK3CA through PIK3R1 (Homo sapiens)
p-6Y FLT3 ITD mutant dimers:GRB2:p-Y GAB2:PI3K [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:p-Y GAB2:PIK3R1 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:p-Y GAB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:p-Y GAB2:PIK3R1 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:p-Y GAB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
FLT3 mutants recruit PIK3R1 through phosphorylated GAB2 (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:p-Y GAB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:p-Y GAB2:PIK3R1 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:p-Y GAB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
FLT3 mutants:GRB2 bind GAB2 (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:GAB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
FLT3 mutants:GRB2:SOS1-mediated nucleotide exchange on RAS (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:SOS1 [plasma membrane] (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
FLT3 mutants:GRB2:p-Y-GAB2 binds PTPN11 (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:p-Y GAB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:p-Y GAB2:PTPN11 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2:p-Y GAB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 mutant dimers:GRB2 [plasma membrane] (Homo sapiens)
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
p-6Y juxtamembrane domain mutant dimers of FLT3 [plasma membrane] (Homo sapiens)
Participants
members
p-6Y FLT3 F590G Y591D dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 F594L dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 V579A dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 V592A dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 V592G dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 Y591_V592insVDFREYEYDH dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 Y597_E598insDEYFYVDFREY dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 D600_L601insMGMGGECNPGRQ dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 K602_W603insYEYDLK dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 W603_E604insSSSDNEYFYVDFREYEYDLKW dimer [plasma membrane]
(Homo sapiens)
p-6Y-FLT3 N609_L610insCSSDNEYFYVDFREYEYDLKWEFPREN dimer [plasma membrane]
(Homo sapiens)
p-6Y-FLT3 F590_F605dup dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 E598_Y599insGLVQVTGSSDNEYFYVDFREYE dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 F612_G613insCSSDNEYFYVDFREYEYDLKWEFPRENL dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 L610_E611insC22DNEYFYVDFREYEYDLKWEFPRENL dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 Y599_D600insGLYVDFREYEY dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 E598_Y599insFDFREYE dimer [plasma membrane]
(Homo sapiens)
p-6Y-FLT3 Y599_G613dup dimer [plasma membrane]
(Homo sapiens)
p-6Y-FLT3 R595_L601dup dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 Y591_V592insVDFREDREHH dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 Y589_F590insFYVDFREYEYDLKWEF dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 E598_Y599insFYVDFREY dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 E598_Y599insVDFREYE dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 L610_E611insLKWEFPRENL dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 E596_Y597insRTDFRE dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 E611_F612insGDNEYFYVDFREYEYDLKWEFPRENLE dimer [plasma membrane]
(Homo sapiens)
candidates
p-6Y FLT3 F594I dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 F594S dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 F594V dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 V579E dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 V579I dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 V579L dimer [plasma membrane]
(Homo sapiens)
p-6Y FLT3 V592D dimer [plasma membrane]
(Homo sapiens)
Participates
as a member of
p-6Y FLT3 extracellular domain, kinase domain and juxtamembrane domain mutant dimers [plasma membrane] (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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