Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
SWAP70 [cytosol]
Stable Identifier
R-HSA-9690929
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Switch-associated protein 70, SWP70_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GEFs activate RAC1 (Homo sapiens)
RAC1 GEFs [cytosol] (Homo sapiens)
SWAP70 [cytosol] (Homo sapiens)
RAC1 binds effectors at the plasma membrane (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
SWAP70 [cytosol] (Homo sapiens)
RAC1:GTP:RAC1 effectors [plasma membrane] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
SWAP70 [cytosol] (Homo sapiens)
RAC2 GTPase cycle (Homo sapiens)
RAC2 GEFs activate RAC2 (Homo sapiens)
RAC2 GEFs [cytosol] (Homo sapiens)
SWAP70 [cytosol] (Homo sapiens)
RAC3 GTPase cycle (Homo sapiens)
RAC3 binds effectors at the plasma membrane (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
SWAP70 [cytosol] (Homo sapiens)
RAC3:GTP:RAC3 effectors [plasma membrane] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
SWAP70 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UH65 SWAP70
Gene Names
SWAP70, KIAA0640, HSPC321
Chain
chain:1-585
Reference Genes
BioGPS Gene:23075 SWAP70
COSMIC (genes):SWAP70 SWAP70
CTD Gene:23075 SWAP70
dbSNP Gene:23075 SWAP70
ENSEMBL:ENSG00000133789 SWAP70
HGNC:17070 SWAP70
Monarch:23075 SWAP70
NCBI Gene:23075 SWAP70
OMIM:604762 SWAP70
UCSC:Q9UH65 SWAP70
Reference Transcript
RefSeq:NM_015055.3 SWAP70
RefSeq:NM_001297714.1 SWAP70
Other Identifiers
11721500_at
11721501_x_at
11721502_at
11757598_s_at
16721861
209306_PM_s_at
209306_s_at
209307_PM_at
209307_at
210369_PM_at
210369_at
23075
31869_at
3319998
3319999
3320000
3320005
3320006
3320008
3320009
3320011
3320012
3320015
3320017
3320019
3320020
3320021
3320022
3320024
3320025
3320026
3320028
3320029
3320030
3320031
3320032
3320033
3320034
3320045
7938370
A_14_P103999
A_14_P106179
A_14_P136192
A_23_P116533
A_24_P359165
A_33_P3349651
GE574724
GO:0002376
GO:0003677
GO:0005085
GO:0005509
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005856
GO:0005886
GO:0006310
GO:0007204
GO:0008064
GO:0015629
GO:0016444
GO:0030027
GO:0030835
GO:0032233
GO:0032880
GO:0033633
GO:0042995
GO:0043226
GO:0045190
GO:0045296
GO:0051017
GO:0051056
GO:0060754
GO:0098772
GO:0098794
GO:1902309
HMNXSV003041040
HMNXSV003053799
Hs.153026.0.A3_3p_a_at
Hs.153026.0.A4_3p_at
ILMN_1785175
PH_hs_0009203
TC11000175.hg
g13111791_3p_at
Participates
as a candidate of
RAC2 GEFs [cytosol] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
as a member of
RAC1 GEFs [cytosol] (Homo sapiens)
Inferred To
SWAP70 [cytosol]
(Bos taurus)
SWAP70 [cytosol]
(Canis familiaris)
SWAP70 [cytosol]
(Dictyostelium discoideum)
SWAP70 [cytosol]
(Gallus gallus)
SWAP70 [cytosol]
(Sus scrofa)
Swap70 [cytosol]
(Mus musculus)
Swap70 [cytosol]
(Rattus norvegicus)
swap70b [cytosol]
(Danio rerio)
Cross References
ENSEMBL
ENST00000318950
,
ENSP00000315630
OpenTargets
ENSG00000133789
HPA
ENSG00000133789-SWAP70
PRO
Q9UH65
Pharos - Targets
Q9UH65
GlyGen
Q9UH65
HMDB Protein
HMDBP11474
PDB
2DN6
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8WZA2 RAPGEF4
1
RAPGEF4 [plasma membrane]
(R-HSA-3008666)
0.666
4
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text