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STK10 [cytosol]
Stable Identifier
R-HSA-9690312
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Serine/threonine-protein kinase 10 ecNumber2.7.11.1/ecNumber, STK10_HUMAN, LOK, Lymphocyte-oriented kinase
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA binds effectors at the plasma membrane (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
STK10 [cytosol] (Homo sapiens)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
STK10 [cytosol] (Homo sapiens)
RHOB GTPase cycle (Homo sapiens)
RHOB binds effectors at the plasma membrane (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
STK10 [cytosol] (Homo sapiens)
RHOB:GTP:cytosolic RHOB effectors [plasma membrane] (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
STK10 [cytosol] (Homo sapiens)
RHOC GTPase cycle (Homo sapiens)
RHOC binds effectors at the plasma membrane (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
STK10 [cytosol] (Homo sapiens)
RHOC:GTP:RHOC effectors [plasma membrane] (Homo sapiens)
RHOC effectors [cytosol] (Homo sapiens)
STK10 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O94804 STK10
Gene Names
STK10, LOK
Chain
chain:1-968
Reference Genes
BioGPS Gene:6793 STK10
COSMIC (genes):STK10 STK10
CTD Gene:6793 STK10
dbSNP Gene:6793 STK10
ENSEMBL:ENSG00000072786 STK10
ENSEMBL:ENSG00000072786.13 STK10
HGNC:11388 STK10
KEGG Gene (Homo sapiens):6793 STK10
Monarch:6793 STK10
NCBI Gene:6793 STK10
OMIM:603919 STK10
UCSC:O94804 STK10
Reference Transcript
RefSeq:NM_005990.3 STK10
Other Identifiers
11717217_at
11717218_a_at
17002777
203047_PM_at
203047_at
228394_PM_at
228394_at
2887049
2887050
2887051
2887052
2887053
2887054
2887056
2887058
2887060
2887062
2887064
2887067
2887071
2887072
2887075
2887076
2887080
2887083
2887087
2887088
2887089
2887097
2887100
2887105
2887118
2887119
40420_PM_at
40420_at
4884305_3p_s_at
64153_at
6793
8115783
91030_at
A_33_P3389153
GE53417
GO:0000166
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005737
GO:0005829
GO:0005886
GO:0006468
GO:0007049
GO:0007155
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0031410
GO:0035579
GO:0036211
GO:0042802
GO:0042803
GO:0043226
GO:0046777
GO:0048870
GO:0070062
GO:0071593
GO:0106310
GO:0140096
GO:2000401
HMNXSV003005959
Hs.24222.0.A1_3p_at
ILMN_1651692
PH_hs_0001488
TC05002059.hg
Participates
as a member of
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
as a candidate of
RHOC effectors [cytosol] (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
Other forms of this molecule
STK10 [plasma membrane]
STK10 [specific granule membrane]
Inferred To
gck-4 [cytosol]
(Caenorhabditis elegans)
STK10 [cytosol]
(Canis familiaris)
STK10 [cytosol]
(Danio rerio)
STK10 [cytosol]
(Drosophila melanogaster)
STK10 [cytosol]
(Gallus gallus)
STK10 [cytosol]
(Mus musculus)
STK10 [cytosol]
(Rattus norvegicus)
STK10 [cytosol]
(Schizosaccharomyces pombe)
STK10 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_005981.3
ZINC - World Drugs
STK10_HUMAN
Guide to Pharmacology - Targets
2211
OpenTargets
ENSG00000072786
ZINC - FDA approved
STK10_HUMAN
ZINC - Substances
STK10_HUMAN
ZINC - Biogenic
STK10_HUMAN
ZINC target
O94804
PRO
O94804
PDB
4USD
,
4USE
,
4BC6
,
5AJQ
,
6HXF
,
5OWQ
,
6I2Y
,
5OWR
,
2J7T
,
6EIM
,
4AOT
,
7QGP
,
6GTT
,
4EQU
ZINC - Investigational
STK10_HUMAN
IntEnz
2.7.11.1
HPA
ENSG00000072786-STK10
GeneCards
O94804
Ensembl
ENSP00000176763
,
ENSG00000072786
,
ENST00000176763
Pharos - Targets
O94804
ZINC - Predictions - Purchasable
STK10_HUMAN
HMDB Protein
HMDBP01266
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