Reactome | TMPRSS2 [plasma membrane]

Stable Identifier

R-HSA-9686707

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Transmembrane protease serine 2 ecNumber3.4.21.-/ecNumber, TMPS2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O15393 TMPRSS2

Gene Names

TMPRSS2, PRSS10

Chain

chain:1-255, chain:256-492

Reference Genes

COSMIC (genes):TMPRSS2 TMPRSS2

dbSNP Gene:7113 TMPRSS2

ENSEMBL:ENSG00000184012 TMPRSS2

Participates

as an input of

Other forms of this molecule

TMPRSS2 [extracellular region]

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P01009 SERPINA1	8	SERPINA1 [endoplasmic reticulum lumen] (R-HSA-8956709) p-SERPINA1 [endoplasmic reticulum lumen] (R-HSA-8957062) SERPINA1 [ficolin-1-rich granule lumen] (R-HSA-6804783) SERPINA1 [extracellular region] (R-HSA-141757) (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (R-HSA-5689435) (Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle] (R-HSA-5689731) (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5689734) SERPINA1 [platelet alpha granule lumen] (R-HSA-141755)	0.558	2
UniProt:Q9BYF1 ACE2	5	glycosylated-ACE2 [plasma membrane] (R-HSA-9683480) ACE2 [endocytic vesicle membrane] (R-HSA-9698958) glycosylated-ACE2 [endocytic vesicle membrane] (R-HSA-9686721) ACE2 [endoplasmic reticulum lumen] (R-HSA-9683474) ACE2(18-805) [plasma membrane] (R-HSA-2022344)	0.463	3

Cite Us!