Polyadenylation of SARS-CoV-1 genomic RNA (plus strand)

Stable Identifier
R-HSA-9685519
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Human SARS coronavirus
Compartment
cytosol
ReviewStatus
5/5
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Polyadenylation of SARS-CoV-1 genomic RNA (plus strand)
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SARS-CoV-1 plus strand genomic RNA, like genomic RNAs of other coronaviruses, possesses a polyadenylation signal in its 3'UTR and is polyadenylated by an undetermined viral RNA polymerase, possibly nsp8 or nsp12 (Spagnolo and Hogue 2000, Peng et al. 2016, Tvarogova et al. 2019).
Literature References
PubMed ID Title Journal Year
27760233 Characterization of the Role of Hexamer AGUAAA and Poly(A) Tail in Coronavirus Polyadenylation

Wu, HY, Tsai, TL, Lin, CN, Lin, CH, Lo, CY, Peng, YH

PLoS ONE 2016
Participants
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Output
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Disease
Name Identifier Synonyms
severe acute respiratory syndrome DOID:2945 SARS-CoV infection, SARS
Authored
Orlic-Milacic, M  (2020-04-30)
Reviewed
Acencio, ML  (2020-05-27)
Mazein, A  (2020-05-27)
Created
Orlic-Milacic, M  (2020-04-23)
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