mRNA1 is translated to pp1a

Stable Identifier
R-HSA-9684301
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Human SARS coronavirus
Compartment
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SVG |   | PPTX  | SBGN
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In most translation attempts the genomic viral mRNA1 in the cytosol is translated to a shortened polyprotein, pp1a (4,382 aa), that does not contain genome replication enzymes (Baranov et al, 2005).

Literature References
PubMed ID Title Journal Year
15680415 Programmed ribosomal frameshifting in decoding the SARS-CoV genome

Baranov, PV, Henderson, CM, Anderson, CB, Gesteland, RF, Atkins, JF, Howard, MT

Virology 2005
Participants
Participant Of
Disease
Name Identifier Synonyms
severe acute respiratory syndrome 2945 SARS-CoV infection, SARS
Authored
Reviewed
Created
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