mRNA1 is translated to pp1ab

Stable Identifier
R-HSA-9684277
Type
Reaction [omitted]
Species
Homo sapiens
Related Species
Human SARS coronavirus
Compartment
cytosol
ReviewStatus
5/5
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mRNA1 is translated to pp1ab
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In about 15% of translation attempts of the genomic viral mRNA1 in the host cell cytosol, a -1 frameshift happens after the nsp10 gene that leads to translation of the full 7,033 aa pp1ab polyprotein (Baranov et al, 2005).
Literature References
PubMed ID Title Journal Year
15680415 Programmed ribosomal frameshifting in decoding the SARS-CoV genome

Baranov, PV, Atkins, JF, Henderson, CM, Howard, MT, Gesteland, RF, Anderson, CB

Virology 2005
Participants
Input
Output
Participates
as an event of
Orthologous Events
mRNA1 is translated to pp1ab (Homo sapiens)
Disease
Name Identifier Synonyms
severe acute respiratory syndrome DOID:2945 SARS-CoV infection, SARS
Authored
Stephan, R  (2020-04-14)
Reviewed
Acencio, ML  (2020-05-27)
Mazein, A  (2020-05-27)
Created
Stephan, R  (2020-04-21)
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