nsp3-4 is glycosylated

Stable Identifier
R-HSA-9684275
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Human SARS coronavirus
Compartment
cytosol, endoplasmic reticulum membrane
ReviewStatus
5/5
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nsp3-4 is glycosylated
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
To process the nsp3/4 cleavage site, PL-PRO and, presumably, nsp3-4 need to be glycosylated and localized to a membrane (Harcourt et al, 2004)
Literature References
PubMed ID Title Journal Year
15564471 Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity

Harcourt, BH, Jukneliene, D, Kanjanahaluethai, A, Bechill, J, Severson, KM, Smith, CM, Rota, PA, Baker, SC

J. Virol. 2004
Participants
Input
Output
Participates
as an event of
Orthologous Events
nsp3-4 is glycosylated (Homo sapiens)
Disease
Name Identifier Synonyms
severe acute respiratory syndrome DOID:2945 SARS-CoV infection, SARS
Cross References
Mondo
Authored
Stephan, R  (2020-04-14)
Reviewed
Acencio, ML  (2020-05-27)
Mazein, A  (2020-05-27)
Created
Stephan, R  (2020-04-21)
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