Maturation of protein E

Stable Identifier
R-HSA-9683683
Type
Pathway
Species
Homo sapiens
Related Species
Human SARS coronavirus
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The envelope protein (E) gets palmitoylated and ubiquitinated after translation. It forms trimers that show porin activity but does not localize to the cell membrane (Tan et al, 2004; Liao et al, 2006; Alvarez et al, 2011).

Literature References
PubMed ID Title Journal Year
16507314 Biochemical and functional characterization of the membrane association and membrane permeabilizing activity of the severe acute respiratory syndrome coronavirus envelope protein

Liao, Y, Yuan, Q, Torres, J, Tam, JP, Liu, DX

Virology 2006
15522242 Expression of SARS-coronavirus envelope protein in Escherichia coli cells alters membrane permeability

Liao, Y, Lescar, J, Tam, JP, Liu, DX

Biochem. Biophys. Res. Commun. 2004
20409569 The envelope protein of severe acute respiratory syndrome coronavirus interacts with the non-structural protein 3 and is ubiquitinated

Alvarez, E, DeDiego, ML, Nieto-Torres, JL, Jiménez-Guardeño, JM, Marcos-Villar, L, Enjuanes, L

Virology 2010
Participants
Participant Of
Disease
Name Identifier Synonyms
severe acute respiratory syndrome 2945 SARS-CoV infection, SARS
Authored
Reviewed
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