Maturation of protein 3a

Stable Identifier
R-HSA-9683673
Type
Pathway
Species
Homo sapiens
Related Species
Human SARS coronavirus
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Maturation of protein 3a
Click the image above or here to open this pathway in the Pathway Browser
Protein 3a is associated with protein M and is found in the virion, although its function in the structure seems non-essential. 3a is O-glycosylated and forms a homotetramer with porin function (Oostra et al, 2006; Lu et al, 2006).
Literature References
PubMed ID Title Journal Year
16894145 Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release

Lu, W, Zheng, BJ, Xu, K, Schwarz, W, Du, L, Wong, CK, Chen, J, Duan, S, Deubel, V, Sun, B

Proc. Natl. Acad. Sci. U.S.A. 2006
16474139 Glycosylation of the severe acute respiratory syndrome coronavirus triple-spanning membrane proteins 3a and M

Oostra, M, de Haan, CA, de Groot, RJ, Rottier, PJ

J. Virol. 2006
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
viral protein processing (0019082)
Orthologous Events
Maturation of protein 3a (Homo sapiens)
Disease
Name Identifier Synonyms
severe acute respiratory syndrome DOID:2945 SARS-CoV infection, SARS
Cross References
Mondo
Authored
Stephan, R  (2020-04-08)
Reviewed
Acencio, ML  (2020-05-27)
Mazein, A  (2020-05-27)
Created
Stephan, R  (2020-04-17)
Cite Us!