GSK3B phosphorylates Ncap

Stable Identifier
R-HSA-9683664
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Human SARS coronavirus
Compartment
Synonyms
Phosphorylation of nucleoprotein
Locations in the PathwayBrowser
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The majority of nucleoprotein is serine-phosphorylated in the cytosol and, possibly, in the nucleus where it gets immediately transported to the cytosol. Phosphorylation is catalyzed by glycogen synthase kinase 3 (GSK3) and several other host cell kinases (Surjit et al, 2005; Wu et al. 2009).

Literature References
PubMed ID Title Journal Year
16103198 The severe acute respiratory syndrome coronavirus nucleocapsid protein is phosphorylated and localizes in the cytoplasm by 14-3-3-mediated translocation

Surjit, M, Kumar, R, Mishra, RN, Reddy, MK, Chow, VT, Lal, SK

J. Virol. 2005
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of GSK3B [cytosol]
Physical Entity
Activity
This event is regulated
Negatively by
Disease
Name Identifier Synonyms
severe acute respiratory syndrome 2945 SARS-CoV infection, SARS
Authored
Created
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