mRNA3 is translated to protein 3a

Stable Identifier
R-HSA-9683618
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Human SARS coronavirus
Compartment
endoplasmic reticulum lumen
ReviewStatus
5/5
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mRNA3 is translated to protein 3a
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There is a mixed population of mRNA3 clones having six, seven, eight and nine T stretches located 14 nt downstream of the initiation codon that occur in vivo. The transcribed Us practically act as slippery sequences in heterogenous ORFs. Translation efficiency is reduced in slipping clones, however (Thiel et al, 2003; Tan et al, 2005; Wang et al, 2006).
Literature References
PubMed ID Title Journal Year
12917450 Mechanisms and enzymes involved in SARS coronavirus genome expression

Rabenau, H, Schelle, B, Hertzig, T, Ivanov, KA, Gorbalenya, AE, Putics, Á, Bayer, S, Ziebuhr, J, Thiel, V, Doerr, HW, Weißbrich, B, Snijder, EJ

J. Gen. Virol. 2003
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
severe acute respiratory syndrome DOID:2945 SARS-CoV infection, SARS
Authored
Stephan, R  (2020-04-08)
Reviewed
Acencio, ML  (2020-05-27)
Mazein, A  (2020-05-27)
Created
Stephan, R  (2020-04-17)
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