Maturation of nucleoprotein

Stable Identifier
R-HSA-9683610
Type
Pathway
Species
Homo sapiens
Related Species
Human SARS coronavirus
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Nucleoprotein, the most abundant viral protein expressed during infection, is found in the cytosol and plasma membrane. After phosphorylation and sumoylation it trimerizes and is moved to the Golgi, the virion budding site (Li et al, 2005; Surjit et al, 2005).

Literature References
PubMed ID Title Journal Year
16103198 The severe acute respiratory syndrome coronavirus nucleocapsid protein is phosphorylated and localizes in the cytoplasm by 14-3-3-mediated translocation

Surjit, M, Kumar, R, Mishra, RN, Reddy, MK, Chow, VT, Lal, SK

J. Virol. 2005
15848177 Sumoylation of the nucleocapsid protein of severe acute respiratory syndrome coronavirus

Li, FQ, Xiao, H, Tam, JP, Liu, DX

FEBS Lett. 2005
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Disease
Name Identifier Synonyms
severe acute respiratory syndrome 2945 SARS-CoV infection, SARS
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