Reactome | PLEKHG3 [cytosol]

PLEKHG3 [cytosol]

Stable Identifier

R-HSA-9679580

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Pleckstrin homology domain-containing family G member 3, PH domain-containing family G member 3

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:A1L390 PLEKHG3

Gene Names

PLEKHG3, KIAA0599

Chain

chain:1-1219

Reference Genes

BioGPS Gene:26030 PLEKHG3

COSMIC (genes):PLEKHG3 PLEKHG3

CTD Gene:26030 PLEKHG3

dbSNP Gene:26030 PLEKHG3

ENSEMBL:ENSG00000126822 PLEKHG3

HGNC:20364 PLEKHG3

KEGG:hsa:26030 PLEKHG3

Monarch:26030 PLEKHG3

NCBI Gene:26030 PLEKHG3

OMIM:617940 PLEKHG3

UCSC:A1L390 PLEKHG3

Reference Transcript

Other Identifiers

11748409_a_at

16785410

212821_PM_at

212821_at

212823_PM_s_at

212823_s_at

229952_PM_at

229952_at

26030

3540215

3540216

3540228

3540229

3540230

3540231

3540234

3540235

3540236

3540237

3540238

3540239

3540240

3540241

3540242

3540243

3540244

3540245

3540246

3540256

3540257

3540258

3540259

3540260

3540264

3540265

3540266

3540267

3540268

3540269

3540270

3540271

3540272

3540273

3540274

3540275

3540276

3540277

3540278

3540279

3540280

3540292

3540293

40959_at

7975095

A_14_P103520

A_14_P128220

A_23_P76901

A_32_P311737

A_33_P3304212

GE79262

GO:0003779

GO:0005085

GO:0005737

GO:0005829

GO:0005856

GO:0008092

GO:0030334

GO:0031267

GO:0043226

GO:0051056

GO:0098772

GO:2000114

HMNXSV003052057

Hs.198037.0.A1_3p_a_at

Hs.198037.0.A2_3p_at

Hs.198037.0.A2_3p_x_at

Hs.47431.2.A1_3p_at

ILMN_1780671

PH_hs_0037366

TC14000393.hg

TC14001731.hg

Participates

as a candidate of

as a member of

Inferred To

PLEKHG3 [cytosol] (Bos taurus)

PLEKHG3 [cytosol] (Canis familiaris)

PLEKHG3 [cytosol] (Sus scrofa)

uig-1 [cytosol] (Caenorhabditis elegans)

Plekhg3 [cytosol] (Mus musculus)

Plekhg3 [cytosol] (Rattus norvegicus)

GEFmeso [cytosol] (Drosophila melanogaster)

Cross References

ENSEMBL

ENST00000394691, ENSP00000378183, ENSG00000126822, ENST00000247226, ENSP00000247226

OpenTargets

ENSG00000126822

GeneCards

PLEKHG3

HPA

ENSG00000126822-PLEKHG3

PRO

A1L390

Pharos - Targets

A1L390

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	10