ETV6(1-384)-PDGFRA(552-1089) fusion [plasma membrane]

Stable Identifier
R-HSA-9673898
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Transcription factor ETV6, ETV6_HUMAN
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
17555450 Two novel imatinib-responsive PDGFRA fusion genes in chronic eosinophilic leukaemia

Grand, FH, Clark, A, Curtis, CE, Reiter, A, Minervini, MM, Cross, NC, Perla, G, Musto, P, Murphy, J, Stewart, J

Br. J. Haematol. 2007
External Reference Information
External Reference
UniProt:P41212 ETV6
Gene Names
ETV6, TEL, TEL1
Chain
chain:1-452
Reference Genes
BioGPS Gene:2120 ETV6
COSMIC (genes):ETV6 ETV6
CTD Gene:2120 ETV6
dbSNP Gene:2120 ETV6
ENSEMBL:ENSG00000139083 ETV6
ENSEMBL_homo_sapiens_GENE:ENSG00000139083.11 ETV6
HGNC:3495 ETV6
KEGG Gene (Homo sapiens):2120 ETV6
Monarch:2120 ETV6
NCBI Gene:2120 ETV6
OMIM:600618 ETV6
UCSC:P41212 ETV6
Reference Transcript
Other Identifiers
11743165_at
11743166_at
11743167_at
1638_at
16748407
205585_PM_at
205585_at
2120
225764_PM_at
225764_at
235056_PM_at
235056_at
3405041
3405042
3405100
3405132
3405142
3405152
3405156
3405157
3405162
3405163
3405164
3405175
3405177
38491_at
55594_at
58239_at
7953981
A_14_P113857
A_23_P105264
A_24_P372862
A_33_P3210343
A_33_P3356325
GE79814
GO:0000122
GO:0000785
GO:0000977
GO:0000978
GO:0000981
GO:0001227
GO:0001228
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005694
GO:0005730
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006357
GO:0007296
GO:0012501
GO:0019904
GO:0022008
GO:0022414
GO:0030154
GO:0043226
GO:0043565
GO:0045944
GO:0048856
GO:0071425
GO:0097152
GO:0140110
GO:1990837
HMNXSV003053967
Hs.146381.2.S1_3p_at
Hs.293972.0.S1_3p_at
ILMN_1789596
PH_hs_0034188
TC12003210.hg
U11732_at
g4503610_3p_at
Participates
as a candidate of
as a component of
Other forms of this molecule
p-12Y-ETV6(1-154)-PDGFRB(527-1106) fusion [plasma membrane]
p-11Y-ETV6(1-384)-PDGFRA(552-1089) fusion [plasma membrane]
ETV6(1-154)-PDGFRB(527-1106) fusion [plasma membrane]
ETV6(1-384)-FLT3(569-993) fusion [cytosol]
ETV6(1-301)-FLT3(574-993) fusion [cytosol]
ETV6(1-384)-FLT3(573-993) fusion [cytosol]
ETV6(1-336)insGCS-FLT3(573-993) fusion [cytosol]
ETV6(1-154)insGSFILG-FLT3(573-993) fusion [cytosol]
ETV6(1-384)-p-3Y-FLT3(659-1620) fusion [cytosol]
ETV6(1-301)-p-6Y-FLT3(574-993) fusion [cytosol]
ETV6(1-336)insGCS-p-6Y-FLT3(573-993) fusion [cytosol]
ETV6(1-154)insGSFILG-p-6Y-FLT3(573-993) fusion [cytosol]
ETV6(1-384)-p-6Y-FLT3(573-993) fusion [cytosol]
Modified Residues
Name
Insertion of residues 552 to 1089 at 385 from UniProt:P16234 PDGFRA
Coordinate
385
Disease
Name Identifier Synonyms
hypereosinophilic syndrome DOID:999 Eosinophilic leukocytosis, eosinophilia
Cross References
RefSeq
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
PRO
PDB
HPA
GeneCards
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
Interactors (4)
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