p-12Y-WDR48(1-323)-PDGFRB(559-1106) fusion [cytosol]

Stable Identifier
R-HSA-9673645
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
20085582 Fusion of PDGFRB to two distinct loci at 3p21 and a third at 12q13 in imatinib-responsive myeloproliferative neoplasms

Grand, FH, Hidalgo-Curtis, C, Apperley, JF, Stark, A, Jeng, M, Gotlib, J, Cross, NC, Stark, A, Chase, A

Br. J. Haematol. 2010
External Reference Information
External Reference
UniProt:Q8TAF3 WDR48
Gene Names
WDR48, KIAA1449, UAF1
Chain
chain:1-677
Reference Genes
BioGPS Gene:57599 WDR48
COSMIC (genes):WDR48 WDR48
CTD Gene:57599 WDR48
dbSNP Gene:57599 WDR48
ENSEMBL:ENSG00000114742 WDR48
HGNC:30914 WDR48
KEGG:hsa:57599 WDR48
Monarch:57599 WDR48
NCBI Gene:57599 WDR48
OMIM:612167 WDR48
UCSC:Q8TAF3 WDR48
Reference Transcript
Other Identifiers
11751037_a_at
11763701_a_at
11763702_a_at
11764063_s_at
16939283
221735_PM_at
221735_at
222157_PM_s_at
222157_s_at
2617882
2617884
2617886
2617888
2617896
2617898
2617900
2617906
2617908
2617910
2617914
2617916
2617918
2617920
2617922
2617928
2617930
2617932
2617934
2617936
2617938
2617940
2617942
2617944
2617946
2617950
2617954
2617956
2617960
2617962
2617964
2617966
2617968
2617970
2617972
2617974
2617976
2617978
2617980
43835_at
4850579C_3p_s_at
4869617C_3p_s_at
50343_at
56919_PM_at
56919_at
57599
65591_PM_at
65591_at
8078834
A_23_P80409
A_33_P3297141
GE56870
GE619482
GE776271
GO:0000724
GO:0003677
GO:0003690
GO:0003697
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005764
GO:0005768
GO:0005770
GO:0005773
GO:0005829
GO:0006281
GO:0006310
GO:0006974
GO:0007283
GO:0007338
GO:0008584
GO:0022414
GO:0031410
GO:0035264
GO:0035800
GO:0043130
GO:0043226
GO:0043231
GO:0043588
GO:0046427
GO:0048568
GO:0048705
GO:0048856
GO:0048872
GO:0050679
GO:0072520
GO:0098772
GO:1902525
GO:1905168
HMNXSV003003360
HMNXSV003027501
Hs.109778.0.S1_3p_at
Hs.109778.1.S1_3p_a_at
Hs.109778.1.S1_3p_s_at
ILMN_1762103
PH_hs_0006056
TC03000197.hg
Participates
as a component of
Other forms of this molecule
WDR48 [nucleoplasm]
WDR48(1-323)-PDGFRB(559-1106) fusion [cytosol]
Modified Residues
Name
Insertion of residues 559 to 1106 at 324 from UniProt:P09619 PDGFRB
Coordinate
324
Name
O4'-phospho-L-tyrosine at 1009
Coordinate
1009
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1021
Coordinate
1021
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 579
Coordinate
579
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 581
Coordinate
581
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 716
Coordinate
716
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 740
Coordinate
740
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 751
Coordinate
751
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 763
Coordinate
763
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 771
Coordinate
771
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 775
Coordinate
775
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 778
Coordinate
778
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 857
Coordinate
857
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Disease
Name Identifier Synonyms
myelodysplastic myeloproliferative cancer DOID:4972 Myeloproliferative/Myelodysplastic syndromes, unclassifiable myelodysplastic myeloproliferative disease, Unclassifiable Myeloproliferative/Myelodysplastic syndrome, Myelodysplastic/myeloproliferative disease (morphologic abnormality)
Cross References
OpenTargets
ENSEMBL
HPA
GeneCards
PRO
Pharos - Targets
Orphanet
GlyGen
PDB
Interactors (13)
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