PDGFRA D842V [plasma membrane]

Stable Identifier
R-HSA-9671549
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Alpha platelet-derived growth factor receptor, PGDS_HUMAN
PDGFRA D842V [plasma membrane] icon
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
PDGFRA, PDGFR2, RHEPDGFRA
Chain
signal peptide:1-23, chain:24-1089
Participates
Other forms of this molecule
Modified Residues
Name
L-aspartic acid 842 replaced with L-valine
Coordinate
842
PsiMod
A protein modification that effectively converts a source amino acid residue to an L-valine.
A protein modification that effectively removes or replaces an L-aspartic acid.
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
gastrointestinal stromal tumor DOID:9253 GANT, GIST, Stromal tumor of gastrointestinal tract
Cross References
COSMIC
Interactors (10)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P01127 PDGFB  8 0.733 11
 UniProt:P09619 PDGFRB  3 0.706 5
 UniProt:P04085 PDGFA  1 0.691 6
 UniProt:P00533 EGFR  20 0.683 4
 UniProt:P46108 CRK  1 0.671 4
 UniProt:Q9NRA1 PDGFC      0.656 3
 UniProt:P46109 CRKL  2 0.569 3
 UniProt:Q8N6L0 KASH5      0.556 3
 UniProt:P19174 PLCG1  6 0.544 3
 UniProt:Q8WVM8 SCFD1  1 0.483 2
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