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PI3K:p-KIT mutant dimers [plasma membrane]
Stable Identifier
R-HSA-9670376
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by KIT in disease (Homo sapiens)
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants (Homo sapiens)
KIT mutants:PI3K catalyze synthesis of PIP3 (Homo sapiens)
PI3K:p-KIT mutant dimers [plasma membrane] (Homo sapiens)
Phosphorylated KIT mutants bind PI3K (Homo sapiens)
PI3K:p-KIT mutant dimers [plasma membrane] (Homo sapiens)
Participants
components
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane]
(Homo sapiens)
PI3K alpha [cytosol]
(Homo sapiens)
Participates
as an output of
Phosphorylated KIT mutants bind PI3K (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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