ATRX:DAXX binds to subtelomeric chromosomal regions

Stable Identifier
R-HSA-9670101
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The complex of ATRX (Alpha-thalassemia mental retardation syndrome X-linked) and DAXX (Death domain-associated protein 6) binds to subtelomeric chromosomal regions and plays a role in the recruitment of cohesin to subtelomeric regions and in the regulation of transcription of the noncoding telomeric repeat-containing RNA (TERRA) (Eid et al. 2015).

Literature References
PubMed ID Title Journal Year
26055325 Genetic Inactivation of ATRX Leads to a Decrease in the Amount of Telomeric Cohesin and Level of Telomere Transcription in Human Glioma Cells

Eid, R, Demattei, MV, Episkopou, H, Augé-Gouillou, C, Decottignies, A, Grandin, N, Charbonneau, M

Mol. Cell. Biol. 2015
Participants
Participant Of
Orthologous Events
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