Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Staff
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Staff
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
p7Y-kinase domain KIT mutants [plasma membrane]
Stable Identifier
R-HSA-9669820
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by KIT in disease (Homo sapiens)
Signaling by kinase domain mutants of KIT (Homo sapiens)
Constitutive phosphorylation of kinase domain KIT mutants (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants (Homo sapiens)
Dimerization of STATs downstream of KIT mutants (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STAT dimers [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STATs [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
Disassociation and translocation of STATs to the nucleus downstream of KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STAT dimers [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
JAK2 binds to p-KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs:JAK2 [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
KIT mutants bind GRB2-SOS (Homo sapiens)
p-KIT mutants:GRB2:SOS [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
KIT mutants bind SFKs (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
KIT mutants:PI3K catalyze synthesis of PIP3 (Homo sapiens)
PI3K:p-KIT mutant dimers [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
Phosphorylated KIT mutants bind PI3K (Homo sapiens)
PI3K:p-KIT mutant dimers [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
Phosphorylation of JAK2 downstream of KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs:JAK2 [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
Phosphorylation of STATs downstream of KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2:STATs [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT mutants:p-STATs [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
Recruitment of STATs by KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2:STATs [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2 [plasma membrane] (Homo sapiens)
KIT mutant dimers:SFKs [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
p-KIT mutants:GRB2:SOS catalyzes nucleotide exchange on RAS (Homo sapiens)
p-KIT mutants:GRB2:SOS [plasma membrane] (Homo sapiens)
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
p7Y-kinase domain KIT mutants [plasma membrane] (Homo sapiens)
Participants
members
p7Y-KIT K642E [plasma membrane]
(Homo sapiens)
p7Y-KIT D816V [plasma membrane]
(Homo sapiens)
p7Y-KIT N822K [plasma membrane]
(Homo sapiens)
p6Y-KIT Y823D [plasma membrane]
(Homo sapiens)
candidates
p7Y-KIT K642Q [plasma membrane]
(Homo sapiens)
p-7Y KIT V654A [plasma membrane]
(Homo sapiens)
p-7Y KIT V654E [plasma membrane]
(Homo sapiens)
p7Y-KIT D816A [plasma membrane]
(Homo sapiens)
p7Y-KIT D816E [plasma membrane]
(Homo sapiens)
p7Y-KIT D816F [plasma membrane]
(Homo sapiens)
p7Y-KIT D816H [plasma membrane]
(Homo sapiens)
p7Y-KIT D816N [plasma membrane]
(Homo sapiens)
p7Y-KIT D816Y [plasma membrane]
(Homo sapiens)
p6Y-KIT Y823C [plasma membrane]
(Homo sapiens)
p6Y-KIT Y823N [plasma membrane]
(Homo sapiens)
p7Y-KIT N822D [plasma membrane]
(Homo sapiens)
p7Y-KIT N822H [plasma membrane]
(Homo sapiens)
p7Y-KIT N822I [plasma membrane]
(Homo sapiens)
p7Y-KIT N822S [plasma membrane]
(Homo sapiens)
p7Y-KIT N822T [plasma membrane]
(Homo sapiens)
p7Y-KIT N822Y [plasma membrane]
(Homo sapiens)
p7Y-KIT A829P [plasma membrane]
(Homo sapiens)
Participates
as an output of
Constitutive phosphorylation of kinase domain KIT mutants (Homo sapiens)
as a member of
p7Y-KIT kinase, extracellular and juxtamembrane domain dimers [plasma membrane] (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text