Reactome | DSCC1 [nucleoplasm]

DSCC1 [nucleoplasm]

Stable Identifier

R-HSA-9668907

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Sister chromatid cohesion protein DCC1, DCC1_HUMAN, DCC1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9BVC3 DSCC1

Gene Names

DSCC1, DCC1, UNQ9337/PRO34008

Chain

chain:1-393

Reference Genes

BioGPS Gene:79075 DSCC1

COSMIC (genes):DSCC1 DSCC1

CTD Gene:79075 DSCC1

dbSNP Gene:79075 DSCC1

ENSEMBL:ENSG00000136982 DSCC1

ENSEMBL_homo_sapiens_GENE:ENSG00000136982.6 DSCC1

HGNC:24453 DSCC1

KEGG Gene (Homo sapiens):79075 DSCC1

Monarch:79075 DSCC1

NCBI Gene:79075 DSCC1

OMIM:613203 DSCC1

UCSC:Q9BVC3 DSCC1

Reference Transcript

RefSeq:NM_024094.2 DSCC1

Other Identifiers

11728729_at

11728730_at

11728731_s_at

17080595

219000_3p_s_at

219000_PM_s_at

219000_s_at

3150716

3150717

3150718

3150719

3150720

3150722

3150723

3150724

3150727

3150728

3150729

3150731

3150732

73048_at

74112_at

79075

8152582

GE63328

GO:0000278

GO:0000775

GO:0000785

GO:0003677

GO:0003689

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0006260

GO:0006275

GO:0007049

GO:0007059

GO:0007064

GO:0017116

GO:0031390

GO:0032508

GO:0034088

GO:0034421

GO:0036211

GO:0043226

GO:0140014

GO:0140097

GO:0140657

GO:1900264

HMNXSV003011788

Hs.173310.2.A1_3p_s_at

ILMN_1776577

PH_hs_0015959

TC08001560.hg

g13129095_3p_at

Participates

as an input of

Formation of the CTF18 complex (Homo sapiens)

as a component of

CTF18 complex [nucleoplasm] (Homo sapiens)

Inferred To

DSCC1 [nucleoplasm] (Bos taurus)

DSCC1 [nucleoplasm] (Canis familiaris)

DSCC1 [nucleoplasm] (Dictyostelium discoideum)

DSCC1 [nucleoplasm] (Gallus gallus)

DSCC1 [nucleoplasm] (Mus musculus)

DSCC1 [nucleoplasm] (Sus scrofa)

dscc-1 [nucleoplasm] (Caenorhabditis elegans)

dscc1 [nucleoplasm] (Xenopus tropicalis)

DCC1 [nucleoplasm] (Saccharomyces cerevisiae)

Dmel\CG11788 [nucleoplasm] (Drosophila melanogaster)

dcc1 [nucleoplasm] (Schizosaccharomyces pombe)

Dscc1 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_076999.2

OpenTargets

ENSG00000136982

HPA

ENSG00000136982-DSCC1

GeneCards

Q9BVC3

Ensembl

ENSP00000322180, ENST00000313655, ENSG00000136982

PRO

Q9BVC3

Pharos - Targets

Q9BVC3

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8TBE7 S35G2			0.564	2
UniProt:Q9UMX0 UBQLN1	1	UBQLN1 [cytosol] (R-HSA-8866006)	0.556	3
UniProt:P22607 FGFR3	20	FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853144) FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853131) FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853152) FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853124) FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853125) FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853127) FGFR3 K650T [plasma membrane] (R-HSA-1614411) FGFR3 K650N [plasma membrane] (R-HSA-1614406) FGFR3 K650M [plasma membrane] (R-HSA-1614402) FGFR3 K650Q [plasma membrane] (R-HSA-1614410) FGFR3 A391E [plasma membrane] (R-HSA-1614390) FGFR3 K650E [plasma membrane] (R-HSA-1614400) FGFR3 G380R [plasma membrane] (R-HSA-1614398) FGFR3 G382D [plasma membrane] (R-HSA-2018740) FGFR3 805fs*141 [plasma membrane] (R-HSA-1614387) FGFR3 [plasma membrane] (R-HSA-2038357) FGFR3 S371C [plasma membrane] (R-HSA-1614421) FGFR3 Y373C [plasma membrane] (R-HSA-1614424) FGFR3 G370C [plasma membrane] (R-HSA-1614394) FGFR3 R248C [plasma membrane] (R-HSA-1614419)	0.556	3
UniProt:P35269 GTF2F1	1	GTF2F1 [nucleoplasm] (R-HSA-65565)	0.527	2
UniProt:Q9HCH3 CPNE5			0.527	2
UniProt:P0CG13 CHTF8	1	CHTF8 [nucleoplasm] (R-HSA-9668898)	0.527	3
UniProt:P35249 RFC4	1	RFC4 [nucleoplasm] (R-HSA-68429)	0.527	4
UniProt:P40937 RFC5	1	RFC5 [nucleoplasm] (R-HSA-68427)	0.527	3
UniProt:P40938 RFC3	1	RFC3 [nucleoplasm] (R-HSA-68431)	0.527	3
UniProt:O14735 CDIPT	1	CDIPT [endoplasmic reticulum membrane] (R-HSA-1498749)	0.527	2
UniProt:Q96GM1 PLPPR2	1	LPPR2 [plasma membrane] (R-HSA-6797629)	0.527	2
UniProt:P00740 F9	20	F9(227-461) R384L [plasma membrane] (R-HSA-9668263) 3OHD110-F9(29-461) N43L [endoplasmic reticulum lumen] (R-HSA-9673207) 3OHD110-F9(29-461) N46S [endoplasmic reticulum lumen] (R-HSA-9673232) 3OHD110-F9(29-461) N43Q [endoplasmic reticulum lumen] (R-HSA-9673217) 3OHD110-F9(29-461) N43W [endoplasmic reticulum lumen] (R-HSA-9673235) 12xCbxE-3D-F9(47-461) R191H [extracellular region] (R-HSA-9673404) F9(29-461) R43Q [extracellular region] (R-HSA-9673228) F9(29-461) R43W [extracellular region] (R-HSA-9673213) 12xCbxE-3D-F9(47-461) R191C [extracellular region] (R-HSA-9673391) F9(29-461) R46S [extracellular region] (R-HSA-9673193) 12xCbxE-3D-F9(47-461) R226W [extracellular region] (R-HSA-9673403) F9(29-461) R43L [extracellular region] (R-HSA-9673205) 12xCbxE-3D-F9(47-461) R226Q [extracellular region] (R-HSA-9673415) 12xCbxE-3D-F9(47-461) R226G [extracellular region] (R-HSA-9673418) F9(227-461) G409V [plasma membrane] (R-HSA-9671020) F9(227-461) I443T [plasma membrane] (R-HSA-9670908) F9(227-461) S411G [plasma membrane] (R-HSA-9671021) F9(227-461) G363E [plasma membrane] (R-HSA-9670894) F9(227-461) G363R [plasma membrane] (R-HSA-9670862) F9(227-461) D410H [plasma membrane] (R-HSA-9671007)	0.527	2

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