CST complex formation

Stable Identifier
R-HSA-9668831
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

CTC1, STN1 and TEN1, orthologs of S. cerrevisiae proteins Cdc13, Stn1 and Ten1, respectively, form the CST complex. This evolutionarily conserved complex plays a role in telomere maintenance (Miyake et al. 2009).

Literature References
PubMed ID Title Journal Year
19854130 RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway

Miyake, Y, Nakamura, M, Nabetani, A, Shimamura, S, Tamura, M, Yonehara, S, Saito, M, Ishikawa, F

Mol. Cell 2009
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created
Cite Us!