CST complex formation

Stable Identifier
R-HSA-9668831
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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CST complex formation
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CTC1, STN1 and TEN1, orthologs of S. cerrevisiae proteins Cdc13, Stn1 and Ten1, respectively, form the CST complex. This evolutionarily conserved complex plays a role in telomere maintenance (Miyake et al. 2009).
Literature References
PubMed ID Title Journal Year
19854130 RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway

Miyake, Y, Nakamura, M, Nabetani, A, Shimamura, S, Tamura, M, Yonehara, S, Saito, M, Ishikawa, F

Mol. Cell 2009
Participants
Input
Output
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as an event of
Orthologous Events
CST complex formation (Bos taurus)
CST complex formation (Canis familiaris)
CST complex formation (Gallus gallus)
CST complex formation (Mus musculus)
CST complex formation (Rattus norvegicus)
CST complex formation (Sus scrofa)
Authored
Orlic-Milacic, M  (2019-11-29)
Reviewed
Hayashi, MT  (2020-04-29)
Created
Orlic-Milacic, M  (2019-11-29)
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