Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
STN1 [nucleoplasm]
Stable Identifier
R-HSA-9668821
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
CST complex subunit STN1, STN1_HUMAN
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Chromosome Maintenance (Homo sapiens)
Telomere Maintenance (Homo sapiens)
Extension of Telomeres (Homo sapiens)
Telomere C-strand (Lagging Strand) Synthesis (Homo sapiens)
Polymerase switching on the C-strand of the telomere (Homo sapiens)
RFC binding displaces Pol Alpha on the C-strand of the telomere (Homo sapiens)
CST complex [nucleoplasm] (Homo sapiens)
STN1 [nucleoplasm] (Homo sapiens)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Homo sapiens)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Homo sapiens)
CST complex [nucleoplasm] (Homo sapiens)
STN1 [nucleoplasm] (Homo sapiens)
Telomere C-strand synthesis initiation (Homo sapiens)
CST complex formation (Homo sapiens)
CST complex [nucleoplasm] (Homo sapiens)
STN1 [nucleoplasm] (Homo sapiens)
STN1 [nucleoplasm] (Homo sapiens)
DNA polymerase:primase binds G-strand of the telomere (Homo sapiens)
CST complex [nucleoplasm] (Homo sapiens)
STN1 [nucleoplasm] (Homo sapiens)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Homo sapiens)
CST complex [nucleoplasm] (Homo sapiens)
STN1 [nucleoplasm] (Homo sapiens)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Homo sapiens)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Homo sapiens)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Homo sapiens)
CST complex [nucleoplasm] (Homo sapiens)
STN1 [nucleoplasm] (Homo sapiens)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Homo sapiens)
CST complex [nucleoplasm] (Homo sapiens)
STN1 [nucleoplasm] (Homo sapiens)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Homo sapiens)
CST complex [nucleoplasm] (Homo sapiens)
STN1 [nucleoplasm] (Homo sapiens)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Homo sapiens)
CST complex [nucleoplasm] (Homo sapiens)
STN1 [nucleoplasm] (Homo sapiens)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Homo sapiens)
CST complex [nucleoplasm] (Homo sapiens)
STN1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H668 STN1
Gene Names
STN1, OBFC1
Chain
chain:1-368
Reference Genes
BioGPS Gene:79991 STN1
COSMIC (genes):STN1 STN1
CTD Gene:79991 STN1
dbSNP Gene:79991 STN1
ENSEMBL:ENSG00000107960.11 STN1
HGNC:26200 STN1
KEGG Gene (Homo sapiens):79991 STN1
Monarch:79991 STN1
NCBI Gene:79991 STN1
OMIM:613128 STN1
UCSC:Q9H668 STN1
Reference Transcript
RefSeq:XM_017016669.1 STN1
RefSeq:XM_006717976.3 STN1
RefSeq:XM_017016670.1 STN1
RefSeq:NM_024928.4 STN1
Other Identifiers
11722652_at
11722653_a_at
16718106
219100_PM_at
219100_at
228781_PM_at
228781_at
3304999
3305000
3305001
3305002
3305004
3305006
3305008
3305010
3305012
3305014
3305016
3305018
3305019
3305020
3305021
3305022
3305026
3305027
3305028
3305032
3305034
3305035
3305036
3305038
3305042
3305045
3305046
3305047
3305048
3305049
3305050
3305051
54050_at
57666_at
58356_at
58359_g_at
60055_at
7936134
79991
A_24_P759674
GE625806
GO:0000723
GO:0000781
GO:0001650
GO:0003676
GO:0003677
GO:0003697
GO:0005515
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0005856
GO:0006260
GO:0010833
GO:0016233
GO:0032200
GO:0032211
GO:0032991
GO:0042162
GO:0043047
GO:0043226
GO:0043231
GO:0045111
GO:0045740
GO:1990879
HMNXSV003054385
Hs.62314.0.A1_3p_at
ILMN_1906158
PH_hs_0014107
TC10001636.hg
TC10002814.hg
g13487922_3p_at
p1723
Participates
as an input of
CST complex formation (Homo sapiens)
as a component of
CST complex [nucleoplasm] (Homo sapiens)
Inferred To
Stn1 [nucleoplasm]
(Mus musculus)
Stn1 [nucleoplasm]
(Rattus norvegicus)
stn1 [nucleoplasm]
(Danio rerio)
stn1 [nucleoplasm]
(Xenopus tropicalis)
STN1 [nucleoplasm]
(Bos taurus)
STN1 [nucleoplasm]
(Canis familiaris)
STN1 [nucleoplasm]
(Gallus gallus)
STN1 [nucleoplasm]
(Sus scrofa)
Cross References
RefSeq
XP_016872159.1
,
NP_079204.2
,
XP_016872158.1
,
XP_006718039.1
OpenTargets
ENSG00000107960
GeneCards
Q9H668
HPA
ENSG00000107960-STN1
Ensembl
ENSP00000358779
,
ENST00000224950
,
ENSG00000107960
,
ENST00000369764
,
ENSP00000224950
PRO
Q9H668
Pharos - Targets
Q9H668
Orphanet
22123
PDB
4JQF
,
6W6W
,
4JOI
Interactors (20)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q5SW96 LDLRAP1
2
LDLRAP1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869097)
LDLRAP1 [plasma membrane]
(R-HSA-171143)
0.85
12
UniProt:Q86WV5 TEN1
1
TEN1 [nucleoplasm]
(R-HSA-9668823)
0.837
11
UniProt:Q2NKJ3 CTC1
1
CTC1 [nucleoplasm]
(R-HSA-9668825)
0.711
7
UniProt:Q9NWQ9 CN119
0.601
4
UniProt:Q2NKJ3-1 CTC1
0.593
5
IntAct:EBI-9009305 TELG31
0.558
2
UniProt:Q8TCE9 PPL13
0.556
3
UniProt:Q9NX04 CA109
0.556
5
UniProt:Q9BT92 TCHP
0.556
3
UniProt:Q13064 MKRN3
0.556
3
UniProt:Q99757 TXN2
2
TXN2 [mitochondrial matrix]
(R-HSA-3323048)
2xHC-TXN2 [mitochondrial matrix]
(R-HSA-3323059)
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
UniProt:Q96HA8 NTAQ1
0.556
3
UniProt:Q9H0E2 TOLLIP
4
TOLLIP [cytosol]
(R-HSA-446885)
TOLLIP [azurophil granule lumen]
(R-HSA-6799709)
TOLLIP [extracellular region]
(R-HSA-6800448)
TOLLIP [specific granule lumen]
(R-HSA-6799719)
0.556
3
UniProt:P51687 SUOX
1
SUOX [mitochondrial matrix]
(R-HSA-1614570)
0.556
3
UniProt:Q9P2K3-2 RCOR3
0.556
3
UniProt:Q8N7C3 TRIMM
0.556
3
UniProt:O14773-1 TPP1
0.527
2
UniProt:Q96AP0 ACD
1
ACD [nucleoplasm]
(R-HSA-174889)
0.508
4
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.488
2
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text