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What is Reactome ?
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PRIM1:PRIM2 [nucleoplasm]
Stable Identifier
R-HSA-9668812
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Primase heterodimer
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G1/S Transition (Homo sapiens)
Activation of the pre-replicative complex (Homo sapiens)
DNA polymerase alpha:primase binds at the origin (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
E2F mediated regulation of DNA replication (Homo sapiens)
Inhibition of replication initiation of damaged DNA by RB1/E2F1 (Homo sapiens)
Detection of damage during initiation of DNA synthesis in S-phase (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
S Phase (Homo sapiens)
Synthesis of DNA (Homo sapiens)
DNA replication initiation (Homo sapiens)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
DNA strand elongation (Homo sapiens)
Lagging Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Formation of Processive Complex (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RFC binding displaces Pol Alpha (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Processive synthesis on the lagging strand (Homo sapiens)
Formation of Okazaki fragments (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Formation of the Flap Intermediate (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Removal of the Flap Intermediate (Homo sapiens)
RPA binds to the Flap (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Recruitment of Dna2 endonuclease (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Removal of RNA primer and dissociation of RPA and Dna2 (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Removal of remaining Flap (Homo sapiens)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Leading Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Formation of Processive Complex (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RFC binding displaces Pol Alpha (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Chromosome Maintenance (Homo sapiens)
Telomere Maintenance (Homo sapiens)
Extension of Telomeres (Homo sapiens)
Telomere C-strand (Lagging Strand) Synthesis (Homo sapiens)
Polymerase switching on the C-strand of the telomere (Homo sapiens)
RFC binding displaces Pol Alpha on the C-strand of the telomere (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Homo sapiens)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Telomere C-strand synthesis initiation (Homo sapiens)
DNA polymerase:primase binds G-strand of the telomere (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:DNA primer:G-strand extended telomere:POLA:primase [nucleoplasm] (Homo sapiens)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Homo sapiens)
POLA:primase:G-strand extended telomere end [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
DNA Replication (Homo sapiens)
DNA Replication Pre-Initiation (Homo sapiens)
Activation of the pre-replicative complex (Homo sapiens)
DNA polymerase alpha:primase binds at the origin (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Synthesis of DNA (Homo sapiens)
DNA replication initiation (Homo sapiens)
The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
DNA strand elongation (Homo sapiens)
Lagging Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Formation of Processive Complex (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RFC binding displaces Pol Alpha (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Processive synthesis on the lagging strand (Homo sapiens)
Formation of Okazaki fragments (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Formation of the Flap Intermediate (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Removal of the Flap Intermediate (Homo sapiens)
RPA binds to the Flap (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Recruitment of Dna2 endonuclease (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Removal of RNA primer and dissociation of RPA and Dna2 (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment complex [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Removal of remaining Flap (Homo sapiens)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Processive complex:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Leading Strand Synthesis (Homo sapiens)
Polymerase switching (Homo sapiens)
Formation of Processive Complex (Homo sapiens)
Processive complex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Loading of PCNA - Sliding Clamp Formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RFC binding displaces Pol Alpha (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RFC dissociates after sliding clamp formation (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Homo sapiens)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Homo sapiens)
RNA primer-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Diseases of programmed cell death (Homo sapiens)
Defective pyroptosis (Homo sapiens)
Decitabine triphosphate incorporates into DNA (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:decitabine-DNA primer:origin duplex [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
PRIM1:PRIM2 [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
24637758
Crystallization and preliminary X-ray diffraction analysis of human DNA primase
Tahirov, TH
,
Babayeva, ND
,
Suwa, Y
,
Gu, J
,
Baranovskiy, AG
,
Agarkar, VB
Acta Crystallogr F Struct Biol Commun
2014
Participants
components
PRIM1 [nucleoplasm]
(Homo sapiens)
PRIM2 [nucleoplasm]
(Homo sapiens)
Participates
as a component of
DNA polymerase alpha:primase [nucleoplasm] (Homo sapiens)
Inferred To
PRIM1:PRIM2 [nucleoplasm]
(Bos taurus)
PRIM1:PRIM2 [nucleoplasm]
(Caenorhabditis elegans)
PRIM1:PRIM2 [nucleoplasm]
(Canis familiaris)
PRIM1:PRIM2 [nucleoplasm]
(Dictyostelium discoideum)
PRIM1:PRIM2 [nucleoplasm]
(Drosophila melanogaster)
PRIM1:PRIM2 [nucleoplasm]
(Gallus gallus)
PRIM1:PRIM2 [nucleoplasm]
(Mus musculus)
PRIM1:PRIM2 [nucleoplasm]
(Plasmodium falciparum)
PRIM1:PRIM2 [nucleoplasm]
(Rattus norvegicus)
PRIM1:PRIM2 [nucleoplasm]
(Saccharomyces cerevisiae)
PRIM1:PRIM2 [nucleoplasm]
(Schizosaccharomyces pombe)
PRIM1:PRIM2 [nucleoplasm]
(Sus scrofa)
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