Based on studies in mouse brain and cultured mouse neurons, NBEA (neurobeachin) forms a complex with DLG3 (SAP-102) (Lauks et al. 2012, Farzana et al. 2016). The PH domain in the C-terminus of NBEA is involved in this interaction (Lauks et al. 2012). Based on UniProt reference protein sequence alignment, human NBEA protein is 97% identical with mouse Nbea, while human DLG3 protein is 95% identical with mouse Dlg3.
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