Reactome | ANKLE2 binds PP2A

ANKLE2 binds PP2A

Stable Identifier

R-HSA-9667965

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol, endoplasmic reticulum membrane

ReviewStatus

5/5

Locations in the PathwayBrowser

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Cell Cycle (Homo sapiens)

- Cell Cycle, Mitotic (Homo sapiens)
  - M Phase (Homo sapiens)
    - Mitotic Metaphase and Anaphase (Homo sapiens)
      - Mitotic Anaphase (Homo sapiens)
        
        Nuclear Envelope (NE) Reassembly (Homo sapiens)
        
        Initiation of Nuclear Envelope (NE) Reformation (Homo sapiens)
        
        ANKLE2 binds PP2A (Homo sapiens)

General

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ANKLE2 binds the PP2A complex that contains the B55-alpha regulatory subunit and facilitates BANF1 dephosphorylation (Asencio et al. 2012).

Literature References

PubMed ID	Title	Journal	Year
22770216	Coordination of kinase and phosphatase activities by Lem4 enables nuclear envelope reassembly during mitosis Wallenfang, MR, Mall, M, Davidson, IF, Santarella-Mellwig, R, Ly-Hartig, TB, Asencio, C, Gorjánácz, M, Mattaj, IW	Cell	2012