KCNMA1:KCNMB1 transports potassium ions from the cytosol to the extracellular region

Stable Identifier
R-HSA-9667809
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Big potassium current channels (BK channels, tetramers of KCNMA1:KCNMB1) in outer hair cells (OHCs) open in response to an influx of calcium ions, thereby causing an efflux of potassium ions which hyperpolarizes the OHC and prevents the OHC from contracting (inferred from mouse homologs and rat homologs).

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Catalyst Activity

calcium-activated potassium channel activity of KCNMA1:KCNMB1 [plasma membrane]

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