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F8 light chain thrombin cleavage site variants [extracellular region]
Stable Identifier
R-HSA-9666399
Type
Complex
Species
Homo sapiens
Compartment
extracellular region
Synonyms
FVIII light chain thrombin cleavage site variants
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of hemostasis (Homo sapiens)
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) (Homo sapiens)
Defective factor VIII causes hemophilia A (Homo sapiens)
Defective F8 cleavage by thrombin (Homo sapiens)
F8 variant is not cleaved by thrombin (Homo sapiens)
FVIII variant:vWF multimer [extracellular region] (Homo sapiens)
F8 thrombin cleavage site variant [extracellular region] (Homo sapiens)
F8 light chain thrombin cleavage site variants [extracellular region] (Homo sapiens)
Participants
components
F8 light chain thrombin cleavage site variants [extracellular region]
(Homo sapiens)
factor VIII heavy chain [extracellular region]
(Homo sapiens)
Participates
as a member of
F8 thrombin cleavage site variant [extracellular region] (Homo sapiens)
Disease
Name
Identifier
Synonyms
factor VIII deficiency
DOID:12134
Congenital factor VIII disorder, Subhemophilia, Hemophilia A
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