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ERBB2 TMD/JMD mutants (pertuzumab resistant) [plasma membrane]
Stable Identifier
R-HSA-9665964
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by ERBB2 in Cancer (Homo sapiens)
Drug resistance in ERBB2 TMD/JMD mutants (Homo sapiens)
ERBB2 TMD/JMD mutants do not bind pertuzumab (Homo sapiens)
ERBB2 TMD/JMD mutants (pertuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
ERBB2 TMD/JMD mutants (pertuzumab resistant) [plasma membrane] (Homo sapiens)
Participants
members
ERBB2 V659E [plasma membrane]
(Homo sapiens)
ERBB2 G660D [plasma membrane]
(Homo sapiens)
ERBB2 G660R [plasma membrane]
(Homo sapiens)
ERBB2 Q709L [plasma membrane]
(Homo sapiens)
Participates
as a component of
ERBB2 TMD/JMD mutants (pertuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane] (Homo sapiens)
Disease
Name
Identifier
Synonyms
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
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