ERBB2 binds pertuzumab

Stable Identifier
R-HSA-9665726
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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General
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Pertuzumab is an ERBB2-directed therapeutic antibody that binds to ERBB2 and sterically blocks receptor dimerization and signaling (Franklin et al. 2004).

Literature References
PubMed ID Title Journal Year
15093539 Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex

Franklin, MC, Carey, KD, Vajdos, FF, Leahy, DJ, de Vos, AM, Sliwkowski, MX

Cancer Cell 2004
Participants
Participant Of
Disease
Name Identifier Synonyms
cancer 162 malignant tumor, malignant neoplasm, primary cancer
Authored
Reviewed
Created