Resistance of ERBB2 KD mutants to AEE788

Stable Identifier
R-HSA-9665250
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Resistance of ERBB2 KD mutants to AEE788
Click the image above or here to open this pathway in the Pathway Browser
This pathway describes resistance of ERBB2 KD mutants to tyrosine kinase inhibitor AEE788 (Kancha et al. 2011).
Literature References
PubMed ID Title Journal Year
22046346 Differential sensitivity of ERBB2 kinase domain mutations towards lapatinib

Duyster, J, Kancha, RK, Engh, RA, Peschel, C, Bartosch, N, von Bubnoff, N

PLoS ONE 2011
Participants
Events
Participates
as an event of
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
BioModels Database
Authored
Orlic-Milacic, M  (2019-10-30)
Reviewed
Kancha, RK  (2019-09-16)
Created
Orlic-Milacic, M  (2019-10-30)
Cite Us!