CHRNA9:CHRNA10 binds acetylcholine

Stable Identifier
R-HSA-9663736
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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CHRNA9:CHRNA10 binds acetylcholine
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CHRNA9:CHRNA10, an unusual nicotinic acetylcholine receptor that is blocked (rather than activated) by nicotine, binds acetylcholine that is secreted by efferent neurons of the olivocochlear complex that form synapses with basal regions of outer hair cells (OHCs) (inferred from rat homologs).

Literature References
PubMed ID Title Journal Year
11752216 A novel human nicotinic receptor subunit, alpha10, that confers functionality to the alpha9-subunit

Besnard, F, Charpantier, E, Graham, D, Walker, N, Sgard, F, Caput, D, Bertrand, S, Bertrand, D

Mol. Pharmacol. 2002
Participants
Input
Output
Participates
as an event of
Inferred From
Chrna9:Chrna10 binds acetylcholine (AcCho) (Rattus norvegicus)
Authored
May, B  (2019-10-08)
Reviewed
Dallos, P  (2020-09-14)
Furness, DN  (2020-09-14)
Created
May, B  (2019-10-12)
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