CHRNA9:CHRNA10 binds acetylcholine

Stable Identifier
R-HSA-9663736
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

CHRNA9:CHRNA10, an unusual nicotinic acetylcholine receptor that is blocked (rather than activated) by nicotine, binds acetylcholine that is secreted by efferent neurons of the olivocochlear complex that form synapses with basal regions of outer hair cells (OHCs) (inferred from rat homologs).

Literature References
PubMed ID Title Journal Year
11752216 A novel human nicotinic receptor subunit, alpha10, that confers functionality to the alpha9-subunit

Sgard, F, Charpantier, E, Bertrand, S, Walker, N, Caput, D, Graham, D, Bertrand, D, Besnard, F

Mol. Pharmacol. 2002
Participants
Participates
Inferred From
Authored
Reviewed
Created
Cite Us!