OGG1 D268A [nucleoplasm]

Stable Identifier
R-HSA-9663727
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
OGG1 Asp268Ala
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
11902834 Reciprocal "flipping" underlies substrate recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylase

Bjørås, M, Seeberg, E, Luna, L, Pearl, LH, Barrett, TE

J. Mol. Biol. 2002
External Reference Information
External Reference
UniProt:O15527 OGG1
Gene Names
OGG1, MMH, MUTM, OGH1
Chain
chain:1-345
Reference Genes
BioGPS Gene:4968 OGG1
COSMIC - genes:OGG1 OGG1
CTD Gene:4968 OGG1
dbSNP Gene:4968 OGG1
ENSEMBL:ENSG00000114026 OGG1
HGNC:8125 OGG1
KEGG:hsa:4968 OGG1
Monarch:4968 OGG1
NCBI Gene:4968 OGG1
OMIM:601982 OGG1
UCSC:O15527 OGG1
Reference Transcript
Participates
as a member of
Other forms of this molecule
OGG1 [nucleoplasm]
OGG1 R131G [nucleoplasm]
OGG1 R46L [nucleoplasm]
OGG1 P266fs*139 [nucleoplasm]
OGG1 R131Q [nucleoplasm]
OGG1 R229Q [nucleoplasm]
OGG1 R46Q [nucleoplasm]
OGG1 R154H [nucleoplasm]
OGG1 D268N [nucleoplasm]
SOH-C326-OGG1 S326C [nucleoplasm]
OGG1 K249Q [nucleoplasm]
OGG1 S326C [nucleoplasm]
OGG1 A288V [nucleoplasm]
OGG1 A53T [nucleoplasm]
Modified Residues
Name
L-aspartic acid 268 replaced with L-alanine
Coordinate
268
PsiMod
L-alanine residue [MOD:00010]
A protein modification that effectively converts a source amino acid residue to an L-alanine.
L-aspartic acid removal [MOD:01634]
A protein modification that effectively removes or replaces an L-aspartic acid.
Disease
Name Identifier Synonyms
genetic disease DOID:630
Cross References
RefSeq
Guide to Pharmacology - Targets
ClinGen
OpenTargets
ENSEMBL
Mondo
GeneCards
HPA
PRO
Pharos - Targets
PDB
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