Reactome | GRXCR1 [cytosol]

GRXCR1 [cytosol]

Stable Identifier

R-HSA-9663063

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Glutaredoxin domain-containing cysteine-rich protein 1, GRCR1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:A8MXD5 GRXCR1

Gene Names

GRXCR1, DFNB25

Chain

chain:1-290

Reference Genes

BioGPS Gene:389207 GRXCR1

COSMIC (genes):GRXCR1 GRXCR1

CTD Gene:389207 GRXCR1

dbSNP Gene:389207 GRXCR1

ENSEMBL:ENSG00000215203 GRXCR1

HGNC:31673 GRXCR1

Monarch:389207 GRXCR1

NCBI Gene:389207 GRXCR1

OMIM:613283 GRXCR1

UCSC:A8MXD5 GRXCR1

Reference Transcript

RefSeq:NM_001080476.2 GRXCR1

Other Identifiers

11731287_at

16966430

16966432

2725621

2725622

2725623

2725639

2725641

2725643

2725645

2725647

389207

67354_at

A_24_P495367

GO:0003674

GO:0005515

GO:0005902

GO:0005929

GO:0007605

GO:0030154

GO:0032420

GO:0042491

GO:0043226

GO:0048839

GO:0048856

GO:0050877

GO:0060091

GO:0060118

GO:0060119

GO:0060122

GO:0090102

HMNXSV003009633

ILMN_1793305

PH_hs_0009859

TC04000262.hg

TC04000263.hg

Participates

as a component of

Stereocilium shaft [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENST00000399770, ENSP00000382670

OpenTargets

ENSG00000215203

HPA

ENSG00000215203-GRXCR1

PRO

A8MXD5

Pharos - Targets

A8MXD5

Orphanet

GRXCR1

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13196 ALAS1	2	PXLP-ALAS1 [mitochondrial matrix] (R-HSA-1022086) ALAS1 [mitochondrial matrix] (R-HSA-189438)	0.556	3
UniProt:O00560 SDCBP	3	SDCBP [cytosol] (R-HSA-373639) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [extracellular region] (R-HSA-6806206)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3

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