ADAM17 [Golgi membrane]

Stable Identifier
R-HSA-9662835
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
ADAM 17 metalloprotease, ADAM 17 sheddase, TACE
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P78536 ADAM17
Gene Names
ADAM17, CSVP, TACE
Chain
signal peptide:1-17, propeptide:18-214, chain:215-824
Reference Genes
BioGPS Gene:6868 ADAM17
COSMIC (genes):ADAM17 ADAM17
CTD Gene:6868 ADAM17
dbSNP Gene:6868 ADAM17
ENSEMBL:ENSG00000151694 ADAM17
HGNC:195 ADAM17
KEGG:hsa:6868 ADAM17
Monarch:6868 ADAM17
NCBI Gene:6868 ADAM17
OMIM:603639 ADAM17
UCSC:P78536 ADAM17
Reference Transcript
Other Identifiers
11731109_a_at
11731110_at
11747645_a_at
11762039_at
1226_at
1227_g_at
16894335
205745_PM_x_at
205745_x_at
205746_PM_s_at
205746_s_at
213532_PM_at
213532_at
2539820
2539822
2539823
2539824
2539825
2539826
2539827
2539828
2539829
2539830
2539831
2539832
2539833
2539834
2539835
2539836
2539838
2539839
2539840
2539841
2539842
2539843
2539844
2539845
2539846
2539847
2539849
2539850
2539852
2539855
2539856
2539857
2539862
3925973
3959680
41601_at
6868
7895004
8050190
A_23_P143120
A_24_P157053
A_32_P129621
GE59572
GO:0000139
GO:0001666
GO:0002376
GO:0002446
GO:0002467
GO:0002690
GO:0003824
GO:0004175
GO:0004222
GO:0005112
GO:0005138
GO:0005178
GO:0005515
GO:0005737
GO:0005788
GO:0005829
GO:0005856
GO:0005886
GO:0005911
GO:0005925
GO:0006508
GO:0006509
GO:0007155
GO:0007219
GO:0007220
GO:0008233
GO:0008237
GO:0008284
GO:0009410
GO:0009986
GO:0010820
GO:0015629
GO:0016020
GO:0016324
GO:0016485
GO:0016787
GO:0017124
GO:0019955
GO:0023061
GO:0030154
GO:0030165
GO:0030183
GO:0030307
GO:0030335
GO:0030512
GO:0032496
GO:0032587
GO:0032722
GO:0032760
GO:0033025
GO:0033077
GO:0033627
GO:0035313
GO:0042987
GO:0043120
GO:0043226
GO:0043536
GO:0045121
GO:0045737
GO:0045741
GO:0045742
GO:0046872
GO:0048536
GO:0048856
GO:0048870
GO:0050830
GO:0051128
GO:0051604
GO:0071403
GO:0071679
GO:0098542
GO:0120163
GO:0140096
GO:1900087
GO:1902945
GO:1903265
GO:1905564
HMNXSV003048247
Hs.52438.1.A1_3p_at
ILMN_1765779
ILMN_2121068
PH_hs_0024641
TC02001558.hg
U69611_at
U86755_s_at
g11497003_3p_a_at
g1857672_3p_a_at
Participates
as an output of
as an input of
Other forms of this molecule
ADAM17 [plasma membrane]
ADAM17(215-827) [plasma membrane]
ADAM17(1-214) [Golgi membrane]
ADAM17(215-827) [Golgi membrane]
ADAM17 [endoplasmic reticulum lumen]
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
ZINC - Substances
ZINC target
PRO
GlyGen
PDB
ZINC - Investigational
IntEnz
HPA
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
Interactors (6)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q12959 DLG1  4 0.65 7
 UniProt:P05556 ITGB1  2 0.609 2
 UniProt:P21926 CD9  4 0.597 3
 UniProt:Q13257 MAD2L1  2 0.581 3
 UniProt:Q80WQ6 RHDF2      0.524 2
 UniProt:P13569 CFTR  17 0.483 5
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