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ATP:P2RX4,7 [plasma membrane]
Stable Identifier
R-HSA-9660825
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
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Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Cell recruitment (pro-inflammatory response) (Homo sapiens)
Purinergic signaling in leishmaniasis infection (Homo sapiens)
ATP binds P2RX4,7 (Homo sapiens)
ATP:P2RX4,7 [plasma membrane] (Homo sapiens)
P2RX4,7 binds itself to form trimeric non-selective cation channels (Homo sapiens)
ATP:P2RX4,7 [plasma membrane] (Homo sapiens)
ATP:P2X4,7 trimer [plasma membrane] (Homo sapiens)
ATP:P2RX4,7 [plasma membrane] (Homo sapiens)
General
P2X1 protein readily forms stable trimers and hexamers, suggesting that the intact receptor is a multimer of three or six subunits in heterologous expression systems. However,assembly in native cells may be influenced significantly by associated proteins that are not present in heterologous expression systems.
Participants
components
ATP [extracellular region]
P2RX4,7 [plasma membrane]
(Homo sapiens)
Participates
as a component of
ATP:P2X4,7 trimer [plasma membrane] (Homo sapiens)
as an input of
P2RX4,7 binds itself to form trimeric non-selective cation channels (Homo sapiens)
as an output of
ATP binds P2RX4,7 (Homo sapiens)
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