S-GGC MRAS T68I [plasma membrane]

Stable Identifier
R-HSA-9660514
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Ras-related protein M-Ras, RASM_HUMAN
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
31108500 Activating MRAS mutations cause Noonan syndrome associated with hypertrophic cardiomyopathy

Motta, M, Sagi-Dain, L, Krumbach, OHF, Hahn, A, Peleg, A, German, A, Lissewski, C, Coppola, S, Pantaleoni, F, Kocherscheid, L, Altmüller, F, Schanze, D, Logeswaran, T, Chahrokh-Zadeh, S, Munzig, A, Nakhaei-Rad, S, Cavé, H, Ahmadian, MR, Tartaglia, M, Zenker, M

Hum. Mol. Genet. 2019
External Reference Information
External Reference
Gene Names
MRAS, RRAS3
Chain
chain:1-205, propeptide:206-208
Other Identifiers
0000870735
11716971_a_at
11758360_s_at
11758561_s_at
16946159
206538_at
225185_at
22808
2644566
2644567
2644568
2644569
2644571
2644589
2644603
2644604
2644610
2644611
2644612
2644613
2644614
2644615
2644616
2644617
38540_at
57217_at
8082965
A_14_P112094
A_14_P112544
A_14_P131120
A_23_P377197
A_24_P88850
GE54384
GO:0000166
GO:0003674
GO:0003924
GO:0005515
GO:0005525
GO:0005575
GO:0005886
GO:0007010
GO:0007165
GO:0007265
GO:0007275
GO:0007517
GO:0008150
GO:0016020
GO:0019003
GO:0030036
GO:0030742
GO:0043167
GO:0048856
GO:1990830
Hs.7298.1.A1_3p_at
ILMN_1748881
PH_hs_0016853
TC03000744.hg
Participant Of
Other forms of this molecule
Modified Residues
Name
S-geranylgeranyl-L-cysteine (geranylgeranyl group) at 205
Coordinate
205
Modification
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Name
L-threonine 68 replaced with L-isoleucine
Coordinate
68
PsiMod
A protein modification that effectively converts a source amino acid residue to an L-isoleucine.
A protein modification that effectively removes or replaces an L-threonine.
Disease
Name Identifier Synonyms
Noonan syndrome 3490 Turner's phenotype, karyotype normal (disorder)
Cite Us!